Dopant Enhanced Conjugated Polymer Thin Film for Low-Power, Flexible and Wearable DMMP Sensor.

Conjugated polymer has the potential to be applied on flexible devices as an active layer, but further investigation is still hindered by poor conductivity and mechanical stability. Here, this work demonstrates a dopant-enhanced conductive polymer thin film and its application in dimethyl methylphosphonate (DMMP) sensor. Among five comparable polymers this work employs, poly(bisdodecylthioquaterthiophene) (PQTS12) achieves the highest doping efficiency after doped by FeCl, with the conductivity increasing by about five orders of magnitude.

Vitamin D3 Supplementation Attenuates Surgery-Induced Neuroinflammation and Cognitive Impairment by Regulating NLRP3 Inflammasome in Mice.

Neuroinflammation plays a dominant role in the progression of postoperative cognitive dysfunction (POCD). Vitamin D has been known to have important regulatory functions in inflammation and immune response. The NOD-like receptor protein 3 (NLRP3) is an essential inflammasome in the inflammatory response and could be activated by anesthesia and surgery.

Comparison of different treatment strategies in the management of endogenic caesarean scar pregnancy: a multicentre retrospective study.

Background: The aim of this study was to evaluate the effectiveness and safety of different treatment strategies for endogenic caesarean scar pregnancy (CSP) patients.

Methods: According to Vial's standard, we defined endogenic-type CSP as (1) the gestational sac growing towards the uterine cavity and (2) a greater than 0.3 cm thickness of myometrial tissue at the caesarean scar.

Regional haemodynamic variables and perfusion index in the evaluation of sciatic nerve block: a prospective observational trial.

Objective: We determined whether regional haemodynamics and perfusion index (PI) could be reliable indicators of a successful sciatic nerve block (SNB).

Design: Prospective observational trial.

Setting: A tertiary teaching hospital in China from April 2020 to August 2020.

Ropivacaine Prevents the Activation of the NLRP3 Inflammasome Caused by High Glucose in HUVECs.

Endothelial dysfunction caused by high glucose is recognized as an important event in the pathogenesis of diabetes-related vascular complications. Ropivacaine is considered to have the best safety profile among the commonly used amide local anesthetics, but the extent of its actions remains incompletely understood. Here, we used human umbilical vein endothelial cells exposed to high glucose to explore the effects of ropivacaine on oxidative stress and markers of inflammation.

Distribution and leaching behavior of organophosphorus and brominated flame retardants in soil in Chengdu.

A total of 29 surface farmland soil samples were collected to investigate the spatial distribution and composition characteristics of 13 organophosphorus flame retardants (OPFRs), 11 polybrominated diphenyl ethers (PBDEs), and 8 novel brominated flame retardants (NBFRs) in Chengdu, China. The OPFRs were widely detected in the farmland soil with concentrations ranging from 2.92 to 160 ng g dry weight (dw).

[Effects of the Veterinary Antibiotic Sulfamethazine on NO Emissions and the Associated Microbiological Mechanism in a Rice Field].

Veterinary antibiotics can enter into croplands with animal excrement and can have effects on nitrification and denitrification processes in the agricultural soils. A field experiment was conducted to evaluate the effect of sulfamethazine (SMZ) on NO emissions, nitrification, denitrification, and related functional gene abundances within a paddy field. Five treatments were used in the experiment, namely, no fertilizer and no antibiotics applied (CK), and pig manure used as basal fertilizer plus urea applied as topdressing with the addition of 0, 5, 15, and 30 mg·kg SMZ (SMZ0, SMZ5, SMZ15, and SMZ30, respectively).

Spatial Distribution of Organophosphorus and Brominated Flame Retardants in Surface Water, Sediment, Groundwater, and Wild Fish in Chengdu, China.

The occurrence and spatial distribution of 13 organophosphorus flame retardants (OPFRs), 11 polybrominated diphenyl ethers (PBDEs), and eight novel brominated flame retardants (NBFRs) were investigated in Jinjiang river water, sediment, crucian carp, and groundwater in Chengdu, China. OPFRs were predominant and ubiquitous contaminants in the Jinjiang river water, sediment, groundwater, fish muscle, fish gills, and viscera with concentrations ranging from 19.1 to 533 ng L, 12.

Grain size distribution and exposure evaluation of organophosphorus and brominated flame retardants in indoor and outdoor dust and PM10 from Chengdu, China.

To investigate overall pollution and potential risk of 32 targets (11 PBDEs, 8 NBFRs, and 13 OPFRs) in indoor and outdoor environments, dust and PM10 samples were sampled from non-occupational and occupational zones in Chengdu, China. ∑Cl-OPFRs, BDE-209, and DBDPE were the dominant constitutes in both the non-occupational and occupational dust. Regarding the PM10, no significant differences were found between the kitchen and the living room for studied OPFRs except TDCIPP, and TCEP, TCPP, TEHP, and TCP displayed significant correlation among the kitchen, the living room and personal samples.

Assessment of reactive nitrogen mitigation potential of different nitrogen treatments under direct-seeded rice and wheat cropping system.

The reactive nitrogen (Nr) pollution is a serious environmental problem. A wise application of nitrogen fertilizer is important for mitigating Nr loss. Field experiments were undertaken during the direct-seeded rice and winter-wheat growing seasons from 2014 to 2015 in Nanjing, one of the typical rice-wheat rotation regions in China, to evaluate the potential of different nitrogen fertilizers for mitigating Nr (NO, NH emissions, and NO leaching) losses.

Distribution and risk assessment of metals in water, sediments, and wild fish from Jinjiang River in Chengdu, China.

To evaluate the distribution patterns, degrees of contamination, and ecological risks of 15 metals (Cd, Pb, Sb, Sn, Tl, Mo, Cr, Mn, Ni, Cu, Zn, As, V, Co, and Se), a total of 26 paired water and sediment samples as well as 7 fish samples were collected in Jinjiang River, Chengdu, China. The metal forms of the sediments were analyzed using BCR three-step sequential extraction procedures, and the metal contents of the samples were determined by ICP-MS. Four environmental indices including the geo-accumulation index, bioconcentration factor, biota-sediment accumulation factor, and the potential ecological risk index were calculated to evaluate pollution level and eco-risk of the metals.

Analysis of methylation profiling data of hyperplasia and primary and metastatic endometrial cancers.

Objective: Endometrial cancer is a prevalent cancer, and its metastasis causes low survival rate. This study aims to utilize DNA methylation data to investigate the mechanism of the development and metastasis of endometrial cancer.

Study Design: Methylation profiling data were down-loaded from Gene Expression Omnibus, including 8 hyperplasias, 33 primary and 53 metastatic endometrial cancers.

Long non-coding RNA SNHG1 is an unfavorable prognostic factor and promotes cell proliferation and migration by Wnt/β-catenin pathway in epithelial ovarian cancer.

Long non-coding RNAs (lncRNA) have been shown to serve critical roles in human cancers development, including epithelial ovarian cancer (EOC). Here, we identified a novel lncRNA SNHG1, which was markedly upregulated in human EOC tissues and cell lines. High SNHG1 expression was associated with aggressive clinical features and poor prognosis of EOC patients.

[Assessment of Gaseous Nitrogen (NH and NO) Mitigation After the Application of a Range of New Nitrogen Fertilizers in Summer Maize Cultivation].

In order to evaluate the potential of a range of new nitrogen fertilizers in comparison with the conventional fertilization to mitigate ammonia (NH) and nitrous oxide (NO) emissions, a field experiment was conducted to investigate NH volatilization and NO emissions from the summer maize field and the relevant driving factors under the different nitrogen fertilizer treatments. Five new varieties of nitrogen fertilizers including the urea ammonium (UA), stability urea with dicyandiamide and hydroquinone (UHD), sulfur coated urea (SCU), urea formaldehyde compound fertilizer (UF) and organic fertilizer (OF) were applied in this experiment, and conventional fertilization (compound fertilizer + urea, CK) was used as the control. The nitrogen amount of 300 kg·hm was applied in all treatments.

Inhibition of mammalian target of rapamycin activation in the rostral anterior cingulate cortex attenuates pain-related aversion in rats.

Pain is a complex experience that comprises both sensory and affective dimensions. Mammalian target of rapamycin (mTOR) plays an important role in the modulation of neuronal plasticity associated with the pathogenesis of pain sensation. However, the role of mTOR in pain affect is unclear.

[Nitrogen Loss Through Different Ways in Cropland Under Conventional Fertilization: An In-situ Study of Summer Maize Season in the Middle and Lower Reaches of the Yangtze River].

In order to better understand the characteristics of nitrogen loss through different pathways under conventional fertilization conditions, a field experiment was conducted to investigate the variations of N2O emission, NH3 volatilization, N losses through surface runoff and leaching caused by the application of nitrogen fertilizers during summer maize growing season in the Middle and Lower reaches of the Yangtze River, China. Our results showed that when compound fertilizer was used as basal fertilizer at the nitrogen rate of 150 kg.hm-2, and urea with the same level of fertilizing as topdressing, the N2O emission coefficient in the entire growing season was 3.

[Soil biochemical characteristics in different ecological systems and their relationships with soil respiration and N2O emission].

The biochemical characteristics of soil in different ecological system and their effects on soil respiration (CO2) and nitrous oxide (N2O) emission were investigated by an indoor incubation method. The results showed that the biochemical characteristics of soils in the different ecosystems and CO2 and N2O emissions from different soils greatly varied with each other. In general, the highest abundance of bacteria was found in the orchard soil, the highest abundance of actinomycetes occurred in the meadows and the highest abundance of fungi appeared in the woodlands.

Surgical morbidity and oncologic results after concurrent chemoradiation therapy for advanced cervical cancer.

Objective: To evaluate the surgical morbidity and oncologic results after concurrent chemoradiotherapy (CCRT) followed by completion surgery for advanced cervical carcinoma.

Methods: The present retrospective analysis included 192 patients with advanced cervical cancer (stage IIB-IVA) treated with CCRT followed by surgery and 186 control patients without completion surgery. Disease-free and overall survival rates were compared.

[Effects of typical herbicides on soil respiration and N2O emissions from soil added with different nitrogen fertilizers].

To investigate the effects of typical herbicides on soil respiration and N2O emissions from soil added with different nitrogen fertilizers, a laboratory incubation experiment was carried out using a modified gas chromatograph (Agilent 4890D) method. The results showed that with (NH4)2SO4 amendment, soil respiration and N2O emissions from the Atrazine and Paraquat treatments had no significant difference in comparison to the control (P > 0.05).

Methane and nitrous oxide emissions from rice seedling nurseries under flooding and moist irrigation regimes in Southeast China.

Measurements of methane (CH(4)) and nitrous oxide (N(2)O) fluxes have been extensively taken following rice seedlings transplanted into paddy fields, while little is known about CH(4) and N(2)O fluxes from rice seedling nurseries. Fluxes of CH(4) and N(2)O were simultaneously measured in rice seedling nurseries under the water regimes of continuous flooding and moist irrigation without waterlogging in Southeast China in 2010. Fluxes of CH(4) and N(2)O from continuously flooded nurseries averaged 10.

[Impacts of enhanced UV-B radiation on respiration rate, CH4 and N2O emission fluxes from rice paddy].

To investigate the impacts of enhanced UV-B radiation on respiration rate, CH4 and N2O emission fluxes from soil-rice system, outdoor pot experiment was carried out during the rice growing season in 2004. The enhanced UV-B radiation treatments were simulated by a 20% increase in its intensity. The gas emission fluxes were measured by static chamber-gas chromatograph method.

[Emission inventory of greenhouse gases from agricultural residues combustion: a case study of Jiangsu Province].

Burning of agricultural crop residues was a major source greenhouse gases. In this study, the proportion of crop straws (rice, wheat, maize, oil rape, cotton and soja) in Jiangsu used as household fuel and direct open burning in different periods (1990-1995, 1996-2000, 2001-2005 and 2006-2008) was estimated through questionnaire. The emission factors of CO2, CO, CH4 and NO20 from the above six types of crop straws were calculated by the simulated burning experiment.

[Effects of elevated ultraviolet-B radiation on the chemical composition of wheat straw and the N2O emission from soil amended with the straw].

An outdoor experiment was carried out to investigate the effects of elevated ultraviolet-B radiation on the chemical composition of wheat straw, and an indoor incubation test was conducted to study the effects of the amendment of the straw on soil N2O emission. Outdoor experiment showed that the enhanced UV-B decreased the aboveground biomass of wheat, increased the lignin and total N contents of wheat straw by 94.2% and 12.