Publications by authors named "Jingxue Niu"
Aging-associated renal dysfunction promotes the pathogenesis of chronic kidney disease. Mitochondrial dysfunction in renal tubular epithelial cells is a hallmark of senescence and leads to accelerated progression of renal disorders. Dysregulated calcium profiles in mitochondria contribute to aging-associated disorders, but the detailed mechanism of this process is not clear.
View Article and Find Full Text PDFBackground: Identify key biomarkers to improve the clinical prognosis of patients with advanced and metastatic clear cell renal cell carcinoma (ccRCC) remains an important research topic. Recently, ccRCC has been regarded as a metabolic disease. Pantothenate kinase-1 () has been shown to play an important regulatory role in global metabolism and associates with the pathogenesis of hepatocellular carcinoma.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to explore the relationship between atherosclerotic plaque features and inflammation using advanced imaging techniques (18F-FDG PET/CT and MRI).
- Analyzed data from 31 patients showed that plaques with ruptured or thin fibrous caps and those rich in lipids or hemorrhage indicated higher inflammation, based on target/background ratios (TBR).
- The findings suggest that combining these imaging methods could improve the assessment and classification of carotid atherosclerotic plaques for better diagnosis.