Effects of prolonged cold stress on vascular function in guinea pigs with atherosclerosis.

This study explored the effects of long-term cold stress on aortic vascular function in guinea pigs. Research Methods: Hartley guinea pigs (n=32) were divided into following groups: atherosclerosis (AS), cold stress (CS), and menthol-stimulated (M) and control (C). On days 1, 15, 30, 45, and 60, guinea pigs in the AS, CS, and M groups were intraperitoneally injected with bovine serum albumin.

Preliminary discussion on the mechanism of active components of Radix Aconiti kusnezoffii in the treatment of migraine based on network pharmacology.

To investigate the mechanism of action of Cao Wu in the treatment of migraine from the perspective of network pharmacology. The Swiss Target Prediction Database and CTD database were used to predict the target information of Cao Wu. Human Genome Database gene cards were used to find migraine-related target genes.

Volatile organic compounds for early detection of prostate cancer from urine.

Prostate cancer (PCa) is one of the most common cancers in men worldwide. Early diagnosis of PCa is extremely challenging due to the lack of effective diagnostic methods. The study presented here aims to evaluate whether urine volatile organic compounds (VOCs) can be used as an emerging diagnostic biomarker for PCa.

A Panel of Bile Volatile Organic Compounds Servers as a Potential Diagnostic Biomarker for Gallbladder Cancer.

As no reliable diagnostic methods are available, gallbladder cancer (GBC) is often diagnosed until advanced stages, resulting in a poor prognosis. In the present study, we assessed whether volatile organic compounds (VOCs) could be used as a diagnostic tool for GBC. The VOCs in bile samples collected from 32 GBC patients were detected by gas chromatography-ion mobility spectrometry (GC-IMS), and 54 patients with benign gallbladder diseases (BGD) were used as controls.

Identification of Ophiopogonis Radix from different producing areas by headspace-gas chromatography-ion mobility spectrometry analysis.

Ophiopogonis Radix can be divided into Zhemaidong (ZMD) and Chuanmaidong (CMD). The main planting areas of ZMD are Cixi City and Sanmen county. The quality and price of Ophiopogonis Radix from different producing areas are different.

A modification of the bootstrapping soft shrinkage approach for spectral variable selection in the issue of over-fitting, model accuracy and variable selection credibility.

In this study, we proposed a new computational method stabilized bootstrapping soft shrinkage approach (SBOSS) for variable selection based on bootstrapping soft shrinkage approach (BOSS) which can enhance the analysis of chemical interest from the massive variables among the overlapped absorption bands. In SBOSS, variable is selected by the index of stability of regression coefficients instead of regression coefficients absolute value. In each loop, a weighted bootstrap sampling (WBS) is applied to generate sub-models, according to the weights update by conducting model population analysis (MPA) on the stability of regression coefficients (RC) of these sub-models.

Towards improvement in prediction of iodine value in edible oil system based on chemometric analysis of portable vibrational spectroscopic data.

Iodine value (IV) is a significant parameter to illustrate the quality of edible oil. In this study, three portable spectroscopy devices were employed to determine IV in mixed edible oil system, a new Micro-Electro-Mechanical-System (MEMS) Fourier Transform Infrared Spectrometer (MEMS-FTIR), a MicroNIR1700 and an i-Raman Plus-785S. Quantitative model was built by Partial least squares (PLS) regression model and four variable selection methods were applied before PLS model, which are Monte Carlo uninformative variables elimination (MCUVE), competitive reweighted sampling (CARS), bootstrapping soft shrinkage approach (BOSS) and variable combination population analysis (VCPA).

Superficial and deep changes of histology, texture and particle size distribution in broiler wooden breast muscle during refrigerated storage.

Recently the poultry industry faced an emerging muscle abnormality termed wooden breast (WB), the prevalence of which has dramatically increased in the past few years. Considering the incomplete knowledge concerning this condition and the lack of information on possible variations due to the intra-fillet sampling locations (superficial vs. deep position) and aging of the samples, this study aimed at investigating the effect of 7-d storage of broiler breast muscles on histology, texture, and particle size distribution, evaluating whether the sampling position exerts a relevant role in determining the main features of WB.

Modeling and predicting the effect of temperature on the growth of Proteus mirabilis in chicken.

A predictive model to study the effect of temperature on the growth of Proteus mirabilis was developed. The growth data were collected under several isothermal conditions (8, 12, 16, 20, 25, 30, 35, 40, and 45°C) and were fitted into three primary models, namely the logistic model, the modified Gompertz model, and the Baranyi model. The statistical characteristics to evaluate the models such as R(2), mean square error, and Sawa's Bayesian information criteria (BIC) were used.

[In vitro cytotoxicity test of medical ultrasonic couplant].

The cytotoxicity of medical ultrasonic couplant was tested by MTT assay and agar overlay test. By MTT assay, when the inoculum density was high, the cytotoxicity level was low, or vice versa. The cytotoxicity grade tested by agar overlay was not accord to MTT assay's too.