Carbon Dots and Their Films with Narrow Full Width at Half Maximum Orange Emission.

To obtain carbon dots (CDs) with narrow full width at half maximum (FWHM) and long-wavelength emission, carbon sources with high conjugate sizes and abundant functional groups can be employed to synthesize CDs. In this study, orange-emissive carbon dots (OCDs) were synthesized with phloroglucinol and rhodamine B as precursors. When the molar ratio of them was 30:1, and ethanol was served as the solvent, OCDs with optimized emission wavelength at approximately 580 nm, an FWHM of 30 nm, and a quantum yield (QY) of 27.

Super-Tough, Non-Swelling Zwitterionic Hydrogel Sensor Based on the Hofmeister Effect for Potential Motion Monitoring of Marine Animals.

Hydrogel-based electronic devices in aquatic environments have sparked widespread research interest. Nevertheless, the challenge of developing hydrogel electronics underwater has not been profoundly surmounted because of the fragility and swelling of hydrogels in aquatic environments. In this work, a zwitterionic double network hydrogel comprised of polyvinyl alcohol (PVA), poly(sulfobetaine methacrylate) (PSBMA), and sulfuric acid (HSO) demonstrates super-tough and non-swelling performance.

Flexible Artificial Tactility with Excellent Robustness and Temperature Tolerance Based on Organohydrogel Sensor Array for Robot Motion Detection and Object Shape Recognition.

Hydrogel-based flexible artificial tactility is equipped to intelligent robots to mimic human mechanosensory perception. However, it remains a great challenge for hydrogel sensors to maintain flexibility and sensory performances during cyclic loadings at high or low temperatures due to water loss or freezing. Here, a flexible robot tactility is developed with high robustness based on organohydrogel sensor arrays with negligent hysteresis and temperature tolerance.

Micro-environment triple-responsive hyaluronic acid hydrogel dressings to promote antibacterial activity, collagen deposition, and angiogenesis for diabetic wound healing.

The clinical treatment of chronic diabetic wounds is a long-standing thorny issue. Strategies targeting the diabetic micro-environment have been developed to promote wound healing. However, it remains challenging to reverse the adverse conditions and re-activate tissue regeneration and angiogenesis.

Prediction significance of autophagy-related genes in survival probability and drug resistance in diffuse large B-cell lymphoma.

Background/aims: Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin lymphoma, has significant prognostic heterogeneity. This study aimed to generate a prognostic prediction model based on autophagy-related genes for DLBCL patients.

Methods: Utilizing bioinformatics techniques, we analyzed the clinical information and transcriptome data of DLBCL patients from the Gene Expression Omnibus (GEO) database.

Care intervention on psychological outcomes among patients admitted to intensive care unit: an umbrella review of systematic reviews and meta-analyses.

Background: Numerous studies have explored care interventions to improve the psychological outcome of intensive care unit (ICU) patients, but inconclusive evidence makes it difficult for decision-makers, managers, and clinicians to get familiar with all available literature and find appropriate interventions. This umbrella review aimed to analyze the relationship between care intervention and psychological outcomes of ICU patients based on existing systematic reviews.

Methods: An umbrella review of evidence across systematic reviews and meta-analyses published between 1987 and 2023 was undertaken.

Electrospinning Nanofibers as Stretchable Sensors for Wearable Devices.

Wearable devices attract great attention in intelligent medicine, electronic skin, artificial intelligence robots, and so on. However, boundedness of traditional sensors based on rigid materials unconstrained self-multilayer structure assembly and dense substrate in stretchability and permeability limits their applications. The network structure of the elastomeric nanofibers gives them excellent air permeability and stretchability.

3D printed microstructured ultra-sensitive pressure sensors based on microgel-reinforced double network hydrogels for biomechanical applications.

Hydrogel-based wearable flexible pressure sensors have great promise in human health and motion monitoring. However, it remains a great challenge to significantly improve the toughness, sensitivity and stability of hydrogel sensors. Here, we demonstrate the fabrication of hierarchically structured hydrogel sensors by 3D printing microgel-reinforced double network (MRDN) hydrogels to achieve both very high sensitivity and mechanical toughness.

Fabricating pectin and chitosan double layer coated liposomes to improve physicochemical stability of beta-carotene and alter its gastrointestinal fate.

To improve storage stability and gastrointestinal (GI) stability of liposomes, pectin and chitosan double layer coated liposome (P-C-L) was proposed and optimized using electrostatic deposition technique. The physical-chemical properties and GI fate of the carrier were then investigated in comparison to that of chitosan coated liposomes (C-L) and un-coated liposomes (L). The results showed P-C-L was successfully prepared at 0.

Erasable, Rewritable, and Reprogrammable Dual Information Encryption Based on Photoluminescent Supramolecular Host-Guest Recognition and Hydrogel Shape Memory.

Information encryption technologies are very important for security, health, commodity, and communications, etc. Novel information encryption mechanisms and materials are desired to achieve multimode and reprogrammable encryption. Here, a supramolecular strategy is demonstrated to achieve multimodal, erasable, reprogrammable, and reusable information encryption by reversibly modulating fluorescence.

Supramolecular assemblies of multifunctional microgels for biomedical applications.

Biomedical materials with outstanding biochemical and mechanical properties have great potential in tissue engineering, drug delivery, antibacterial, and implantable devices. Hydrogels have emerged as a most promising family of biomedical materials because of their high water content, low modulus, biomimetic network structures, and versatile biofunctionalities. It is critical to design and synthesize biomimetic and biofunctional hydrogels to meet demands of biomedical applications.

Printable Thermochromic Hydrogel-Based Smart Window for All-Weather Building Temperature Regulation in Diverse Climates.

Thermochromic smart windows are widely developed to modulate building energy exchange to save building energy consumption. However, most smart windows have fixed working temperatures, moderate energy-saving efficiency, and are not suitable for diverse (cold and hot) climates. Here smart windows with strong temperature modulation over a broad range of hydrogels with adjustable transition temperatures for all-weather building temperature regulation in different climates are reported.

One-Step Synthesis of White-Light-Emitting Carbon Dots for White LEDs with a High Color Rendering Index of 97.

White-light-emitting carbon dots (WCDs) show innate advantages as phosphors in white light-emitting diodes (WLEDs). For WLEDs, the color rendering index (CRI) is the most important metric to evaluate its performance. Herein, WCDs are prepared by a facile one-step solvothermal reaction of trimellitic acid and o-phenylenediamine.

Surface state modulation of blue-emitting carbon dots with high quantum yield and high product yield.

In order to explore the surface state modulation mechanism of carbon dots (CDs) with high quantum yield (QY) and high product yield (PY), CDs were synthesized from different carbon sources with different contents of oxygen-containing functional groups and different silane coupling agents with nitrogen-containing functional groups. The highest QY of as-prepared CDs can reach 97.32% and the PY values of CDs are all high ranging from 46.

Carbon dots-based delayed fluorescent materials: Mechanism, structural regulation and application.

Delayed fluorescent (DF) materials have high internal quantum efficiency because of the triplet excitons involved in the radiation transition, and the spin-forbidden transition can effectively improve their luminescent lifetime. Compared with traditional afterglow materials including metal-containing inorganic coordination compounds and organic compounds, the DF materials based on carbon dots (CDs) have drawn extensive attention because of their advantages of low toxicity, environmental friendliness, stable luminescence, easy preparation and low cost. Most CDs-based DF materials can be realized by embedding CDs in matrix with covalent bonds, hydrogen bonds or/and other supramolecular interactions.

Effect of Tongfu traditional Chinese medicine preparation on patients with septic gastrointestinal dysfunction: a systematic review and meta-analysis.

Background: Tongfu traditional Chinese medicine (TCM) preparation is a common alternative therapy for clinical treatment of patients with septic gastrointestinal dysfunction. In recent years, a number of randomized controlled trials (RCTs) have been conducted to verify the effectiveness of Tongfu TCM preparation in the treatment of sepsis gastrointestinal dysfunction, but all of them have been small sample studies, and the research conclusions have been controversial. Here, this study conducted a meta-analysis on the clinical efficacy of the treatment of septic gastrointestinal dysfunction with TCM preparation, to produce a more objective and comprehensive systematic review to guide clinical application.

Consecutive Hypoalbuminemia Predicts Inferior Outcome in Patients With Diffuse Large B-Cell Lymphoma.

The prognostic value of albumin changes between diagnosis and end-of-treatment (EoT) in diffuse large B-cell lymphoma (DLBCL) remains unknown. We retrospectively analyzed 574 DLBCL patients treated with R-CHOP from our and two other centers. All patients were divided into a training cohort (n = 278) and validation cohort (n = 296) depending on the source of the patients.

Facile Preparation of Stable Solid-State Carbon Quantum Dots with Multi-Peak Emission.

Aggregation-caused quenching (ACQ) effect, known as the main cause to restrain solid-state luminescence of carbon quantum dots (CQDs), hinders further application of CQDs in white light-emitting diodes (WLED). Here, a complex of CQDs and phthalimide crystals (CQDs/PC) was prepared through a one-step solvothermal method. CQDs/PC prevented CQDs from touching directly by embedding the CQDs in phthalimide crystal matrix in situ, which effectively reduced the ACQ effect.

Albumin improves stratification in the low IPI risk patients with diffuse large B-cell lymphoma.

Previous studies showed albumin at diagnosis could be used to predict outcome in patients with diffuse large B-cell lymphoma (DLBCL), but whether albumin could improve the international prognostic index (IPI) risk stratification remains unknown. Herein, we retrospectively analyzed 440 de novo DLBCL patients in this study. The cutoff value of albumin was 39.

An Efficient Synthesis and Photoelectric Properties of Green Carbon Quantum Dots with High Fluorescent Quantum Yield.

To greatly improve the production quality and efficiency of carbon quantum dots (CQDs), and provide a new approach for the large-scale production of high-quality CQDs, green carbon quantum dots (g-CQDs) with high product yield (PY) and high fluorescent quantum yield (QY) were synthesized by an efficient one-step solvothermal method with 2,7-dihydroxynaphthalene as the carbon source and ethylenediamine as the nitrogen dopant in this study. The PY and QY of g-CQDs were optimised by adjusting reaction parameters such as an amount of added ethylenediamine, reaction temperature, and reaction duration. The results showed that the maximum PY and QY values of g-CQDs were achieved, which were 70.

Development of Oral Delivery Systems with Enhanced Antioxidant and Anticancer Activity: Coix Seed Oil and β-Carotene Coloaded Liposomes.

Fortifying food and beverage products with combinations of bioactive agents is a major initiative within the food industry because of their potentially additive or even synergistic benefits for human health. Coix seed oil (CSO) has been reported to possess anticancer activity, whereas β-carotene (βC) is a natural antioxidant that may also exhibit anticancer activity. However, both of these bioactives are insoluble in water and have poor oral bioavailability.

One-step hydrothermal synthesis of fluorescence carbon quantum dots with high product yield and quantum yield.

A one-step hydrothermal synthesis of nitrogen and silicon co-doped fluorescence carbon quantum dots (N,Si-CQDs), from citric acid monohydrate and silane coupling agent KH-792 with a high product yield (PY) of 52.56% and high quantum yield (QY) of 97.32%, was developed.

Carbon dot-based white and yellow electroluminescent light emitting diodes with a record-breaking brightness.

First, oleophilic carbon dots (CDs) with a fluorescence quantum yield (QY) of 41% were synthesized by a one-pot microwave-assisted carbonization method. Then, CD-based electroluminescent light emitting diodes (CD-LEDs) were prepared. The impact of CD aggregation on the brightness of CD-LEDs was studied.

The synthesis of green fluorescent carbon dots for warm white LEDs.

Green fluorescent carbon dots (CDs) were synthesized with pyrogallic acid as carbon source by solvothermal method in ,-dimethylformamide (DMF). During the formation of the CDs, DMF not only serves as solvent for reaction, but also as nitrogen source to participate in the reaction. At the same time, it promotes the formation of large conjugated sp-domain in CDs.

A Systematic Review of Rhubarb (a Traditional Chinese Medicine) Used for the Treatment of Experimental Sepsis.

Sepsis is a global major health problem in great need for more effective therapy. For thousands of years, Rhubarb had been used for various diseases including severe infection. Pharmacological studies and trials reported that Rhubarb may be effective in treating sepsis, but the efficacy and the quality of evidence remain unclear since there is no systematic review on Rhubarb for sepsis.