Publications by authors named "Jingting Wan"
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by binding to the 3'-untranslated regions of target mRNAs, influencing various biological processes at the post-transcriptional level. Identifying miRNA transcription start sites (TSSs) and transcription factors' (TFs) regulatory roles is crucial for elucidating miRNA function and transcriptional regulation. miRStart 2.
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- Circular RNAs (circRNAs) are looped RNA molecules that regulate gene expression by acting as sponges for microRNAs and are gaining recognition as potential cancer biomarkers.
- The newly updated CircNet 2.0 integrates circRNAs from various databases, analyzing 2732 samples from 37 cancer types and predicting target microRNAs using reliable computational tools.
- This version of CircNet enhances user experience with an interactive web interface and offers a comprehensive resource for constructing circRNA-miRNA-gene regulatory networks in biomedical research.