Publications by authors named "Jingsi Bai"
Clinical Observation of Acupuncture Combined with Biofeedback Electrical Stimulation in the Treatment of Female Stress Urinary Incontinence.
Appl Psychophysiol Biofeedback
December 2024
Article Synopsis
- - This study explored the effectiveness of combining acupuncture with biofeedback electrical stimulation for treating female stress urinary incontinence, involving 90 patients divided into three different treatment groups.
- - Group A received biofeedback, Group B underwent acupuncture, and Group C received both treatments alongside pelvic floor muscle training, with various assessments before and after treatments.
- - Results showed significant improvement in pelvic floor muscle strength and urinary incontinence in groups receiving biofeedback and acupuncture (A and C), with group C showing the greatest benefits, indicating combined treatments are more effective than either treatment alone.
Article Synopsis
- Development of unnatural base pairs (UBPs), like dNaM-dTPT3, has expanded the genetic alphabet and enabled the creation of semisynthetic cells with six-letter genomes.
- Conventional synthesis methods for oligonucleotides with UBPs often face limitations, such as the need for unstable materials and specialized equipment.
- A new one-pot enzymatic method using Klenow fragment (exo) has been developed to efficiently produce UB-containing oligonucleotides, making the process simpler and more cost-effective for lab applications.
Unnatural base pairs (UBPs) have been developed to expand the genetic alphabet and . UBP dNaM-dTPT3 and its analogues have been successfully used to construct the first set of semi-synthetic organisms, which suggested the great potential of UBPs to be used for producing novel synthetic biological parts. Two prerequisites for doing so are the facile manipulation of DNA containing UBPs with common tool enzymes, including DNA polymerases and ligases, and the easy availability of UBP-containing DNA strands.
View Article and Find Full Text PDFBase excision (BE) is an important yet hard-to-control biological event. Unnatural base pairs are powerful tools to revolutionize biological studies in various areas. In this paper, we report a visible-light-induced method to construct site-specific unnatural BE and show the influence of its regulation on transcription and translation levels.
View Article and Find Full Text PDFPrevious studies have led to opposing hypotheses about the requirement of intermolecular disulfide exchange in the binding of the iron regulatory peptide hepcidin to its receptor ferroportin. To clarify this issue, we used the diaminodiacid approach to replace the disulfide bonds in hepcidin with non-reducible thioether bonds. Our results implied that disulfide exchange is not required for the interaction between hepcidin and ferroportin.
View Article and Find Full Text PDFHistone ubiquitination affects the structure and function of nucleosomes through tightly regulated dynamic reversible processes. The efficient preparation of ubiquitinated histones and their analogs is important for biochemical and biophysical studies on histone ubiquitination. Here, we report the CAACU (cysteine-aminoethylation assisted chemical ubiquitination) strategy for the efficient synthesis of ubiquitinated histone analogs.
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