Tetraiodo Fe/Ni phthalocyanine-based molecular catalysts for highly efficient oxygen reduction reaction and oxygen evolution reaction: Constructing a built-in electric field with iodine groups.

In this paper, we report on the preparation and catalysis of a bifunctional molecular catalyst (Fe[Pc(I)]+Ni[Pc(I)]@NC) for oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) in rechargeable Zn-air batteries. This catalyst is prepared by self-assembling tetraiodo metal phthalocyanines (Fe[Pc(I)] and Ni[Pc(I)]) on a 2D N-doped carbon material (NC) through π-π interactions. The introduction of iodine groups in the edge of phthalocyanines controls the density of electron cloud and electrostatic potential around Fe-N/Ni-N sites and constructs a built-in electric field that facilitates directional transport of charges, enhancing the catalytic activity of the catalyst.

Metalloporphyrin-Based Metal-Organic Frameworks for the Ultrasensitive Chemiresistive Detection of NO: Effect of the Central Metal on Tuning the Sensing Performance.

The highly sensitive and selective detection of trace hazardous gases at room temperature is very promising for health protection and environmental safety. Herein, chemiresistive sensors for NO were fabricated based on self-assembled films of the four metalloporphyrin (MPor)-based metal-organic frameworks PCN-222-M (M = Cu, Ni, Co, Fe) by the quasi-Langmuir-Shäfer method. It is found that the relative responses of the four PCN-222-M films are linearly related to the NO concentration, and the PCN-222-Cu possessed an unprecedented high response to NO with a sensitivity of 2209% ppm in the 4-20 ppb range and a low limit of detection (LOD) of 0.

Neuroprotective effects and dynamic expressions of MMP9 and TIMP1 associated with atorvastatin pretreatment in ischemia-reperfusion rats.

Atorvastatin has been reported to ameliorate ischemic brain damage after stroke, but the underlying mechanisms are not clear. This study investigated the effect of atorvastatin on dynamic expressions of MMP9 and TIMP1 in rats after cerebral ischemia reperfusion (I/R). Atorvastatin (5 mgkg(-1)d(-1)) or vehicle was administered orally to rats for 21d before middle cerebral artery occlusion (MCAo) for 2h, with perfusion at 3-, 12-, 24-, 48-, or 96-h thereafter.

2,5-hexanedione induced apoptosis in mesenchymal stem cells from rat bone marrow via mitochondria-dependent caspase-3 pathway.

2,5-hexanedione (HD) induces apoptosis of nerve cells. However,the mechanism of HD-induced apoptosis remains unknown. Mesenchymal stem cells (MSCs) are multipotential stem cells with the ability to differentiate into various cell types.