Relationship between caregiver burden and family resilience among Chinese parents of children with autism spectrum disorder: The mediating role of social support and positive cognition.

Purpose: This study was designed to assess the impact of caregiver burden on family resilience and explore the potential mediating role of social support and positive cognition in this association among Chinese families of children with autism spectrum disorder (ASD).

Design And Methods: A total of 254 parents of children with ASD were recruited using convenience sampling from five ASD rehabilitation institutions in Wenzhou and Ningbo, Zhejiang Province from June to August 2021. The Zarit Burden Scale, Social Support Rate Scale, Illness Cognition Questionnaire-Parent Version, and Family Resilience Assessment Scale were employed to investigate the mediating mechanisms of social support and illness cognition between caregiver burden and family resilience.

Transitions in patterns of family resilience and their associations with parent-child interaction: A longitudinal study using latent transition analysis among families of children with chronic illness.

Objective: This study aimed to investigate transitions in patterns of family resilience among Chinese families of children with chronic illness over a one-year period, as well as their relationship to parent-child interaction.

Methods: A representative sample of parents of children with chronic illness was drawn from two hospitals in Zhejiang Province, China, using convenience sampling. A total of 214 parents were assessed for family resilience, parent-adolescent communication, and child-parent relationships at three time points with a one-year interval: baseline (T1), 6 months (T2), and 12 months (T3) after the baseline survey.

Effect of 2-Way Social Support and Social Networks on the General Well-Being of Older Adults: A Latent Profile Analysis.

Aims: To examine the profiles of general well-being in older adults and their related sociodemographic characteristics and to explore the association of these profiles with 2-way social support and social networks.

Design: This was a cross-sectional study.

Methods: In total, 411 older adults were recruited through convenience sampling from Zhejiang Province, southeast China.

Trajectories and influencing factors of psychological resilience among Chinese patients with maintenance hemodialysis.

Objective: To identify distinct trajectories of psychological resilience among Chinese patients with maintenance hemodialysis, explore influencing factors and inform the formulation of corresponding interventions.

Methods: This was a multi-center longitudinal study with a 6-month follow-up. With convenience sampling, a total of 231 patients with maintenance hemodialysis were recruited between September 2020 and July 2021.

Neuroprotective effects of exosomes derived from bone marrow mesenchymal stem cells treated by Musk Ketone on ischemic stroke.

Objectives: Ischemic stroke (IS) is a leading cause of morbidity and mortality globally. This study aimed to investigate the role of exosomes (Exo) derived from bone marrow mesenchymal stem cells (BMSCs) treated with Musk Ketone (Mus treated-Exo) in the development of IS injury.

Methods: BMSCs were pretreated with 10 μM Mus for 36 h, and Exo derived from these Mus-treated BMSCs (Mus-treated Exo) were extracted.

Adaptation and validation of the Abrams geriatric self-neglect assessment scale among older Chinese people admitted to the hospital.

Objectives: Elder self-neglect is a global public health problem, and older people admitted to the hospital may have a higher risk of self-neglect due to their deteriorating health conditions. This study aimed to translate, adapt and validate the Abrams geriatric self-neglect assessment scale (AGSS) among older Chinese people admitted to the hospital.

Methods: Data were derived from a cross-sectional survey of a convenience sample of 452 older people admitted to a general hospital.

Mental health associated with the cluster of childhood trauma and resilience among nursing students: A cross-sectional study.

Objective: This study aimed to propose clusters of the association between childhood trauma and resilience in nursing students and to examine their mental health according to these clusters.

Method: A cross-sectional study was carried out between September 2018 and May 2019. A total of 1,245 undergraduate nursing students (104 male, 1,141 female) were enrolled in a medical university in East China to complete the Childhood Trauma Questionnaire, Connor-Davidson Resilience Scale, Self-Rating Anxiety Scale, and Self-Rating Depression Scale.

Tongqiao Huoxue decoction alleviates neurological impairment following ischemic stroke via the PTGS2/NF-kappa B axis.

Traditional Chinese medicine has emerged as promising targets for ischemic stroke (IS) therapy, yet the mechanism remains elusive. The current study was performed with an aim to investigate the action and mechanism of Tongqiao Huoxue decoction (TQHXD) affecting the neurological impairment secondary to IS based on network pharmacology. Based on network pharmacology and bioinformatics analysis, target genes and pathways involved in the treatment of TQHXD against IS were predicted.

Systems Pharmacology-Based Strategy to Investigate the Mechanism of Ruangan Lidan Decoction for Treatment of Hepatocellular Carcinoma.

epatocellular carcinoma (HCC) is one of the leading contributors to cancer mortality worldwide. Currently, the prevention and treatment of HCC remains a major challenge. As a traditional Chinese medicine (TCM) formula, Ruangan Lidan decoction (RGLD) has been proved to own the effect of relieving HCC symptoms.