Publications by authors named "Jingrong Ruan"
Article Synopsis
- Acute myeloid leukemia (AML) is linked to the abnormal activation of the JAK/STAT3 signaling pathway, which can be targeted for treatment.
- Previous research showed that SAR317461, a new JAK2/STAT3 inhibitor, effectively reduces AML cell activity and promotes cell death.
- This project aims to improve SAR317461's delivery to AML cells using CD34 antibody-modified liposomes, enhancing treatment effectiveness by combining it with cytarabine and potentially tackling chemotherapy resistance.
