Intravascular laser speckle imaging catheter for the mechanical evaluation of the arterial wall.

Laser speckle imaging (LSI) is a novel technique for measuring the mechanical properties of atherosclerotic plaques. In LSI, the decorrelation time constant of speckle intensity fluctuations provides an index of viscoelasticity that is closely related to plaque microstructure and composition. Here, we demonstrate for the first time, the feasibility of conducting LSI in vivo using a prototype 1.

Lasing and optical gain around 500 nm from optically pumped lasers grown on c-plane GaN substrates.

Using the variable stripe length method we demonstrated positive net optical gain around 500 nm for an optically pumped laser with InGaN/GaN multiple quantum wells grown on c-plane freestanding GaN substrates. We found that owing to low optical gain, reducing optical losses is crucial to increasing lasing wavelength. We demonstrated lasing at 502 nm by using a 3-mm-long cavity with cleaved facets.