Background: Currently, there is a lack of serum biomarkers that can accurately predict the short-term prognosis of enterogenic sepsis.
Methods: 99 patients with enterogenic sepsis were categorized based on their Acute Gastrointestinal Injury (AGI) grade on the third day of ICU admission into four groups: no AGI, AGI grade I, AGI grade II, and AGI (III+IV). Additionally, patients were classified into survival and death groups according to their 28-day clinical outcomes.
In the realm of energy storage, flexible portable supercapacitors have been receiving increasing attention in the last few years. Nonetheless, the process of choosing appropriate flexible materials remains challenging. Herein, we successfully synthesized a flower-like MnCoO@FeCoNi-LDH/CC (MnCo@FCN/CC) hierarchically nanostructured electrode material by anchoring MnCoO (MnCo) on a flexible carbon cloth (CC) substrate first and then loading FeCoNi-LDH nanosheets on MnCoO.
View Article and Find Full Text PDFTo replace precious metals and reduce production costs for large-scale hydrogen production, developing stable, high-performance transition metal electrocatalysts that can be used in a wide range of environments is desirable yet challenging. Herein, a self-supported hybrid catalyst (NiFeCrS/NF) with high electrocatalytic activity was designed and constructed using conductive nickel foam as a substrate via manipulation of the cation doping ratio of transition metal compounds. Due to the strong coupling synergy between the metal sulfides NiS, FeS, and CrS, as well as their interaction with the conductive nickel foam (NF), the energy barrier for catalytic reactions is reduced, and the charge transfer rate is enhanced.
View Article and Find Full Text PDFCapturing forceful interaction with deformable objects during manipulation benefits applications like virtual reality, telemedicine, and robotics. Replicating full hand-object states with complete geometry is challenging because of the occluded object deformations. Here, we report a visual-tactile recording and tracking system for manipulation featuring a stretchable tactile glove with 1152 force-sensing channels and a visual-tactile joint learning framework to estimate dynamic hand-object states during manipulation.
View Article and Find Full Text PDFIn this Letter, the silicon-based microring resonator (MRR) was experimentally demonstrated for cryogenic sensing down to 10 K by overcoming the issue of acquiring the optical signals at low temperatures for on-chip optical sensors. A wide-range temperature sensor from 240 to 10 K was obtained. The experimental results show that the device sensitivity decreased from 64.
View Article and Find Full Text PDFBinary layered double hydroxides (LDHs) are an emerging class of materials for supercapacitors owing to their tunable topological structure and excellent theoretical energy storage capacity. However, aggregation and restacking cause a decrease in the interlayer distance of LDHs, resulting in a considerable drop in real specific capacitance. To address this, large-sized anions are intercalated into the interlayer space.
View Article and Find Full Text PDFBackground: Enteral nutrition administered via the nasointestinal tube (NET) is a prevalent nutritional modality among critically ill patients, and abdominal radiographs hold significant value in accurately ascertaining the precise positioning of the NET subsequent to its placement. Therefore, we propose an innovative approach to construct a clinical prediction model based on NET's configuration within the gastrointestinal tract in abdominal radiography. This model aims to enhance the accuracy of determining the position of NETs after their placement.
View Article and Find Full Text PDFAcute gastrointestinal injury (AGI) is common in mechanically ventilated (MV) patients, but the potential association between ventilatory pressure parameters and AGI grade and their impact on mortality remains unclear. This study aimed to explore the association between ventilatory pressure parameters and AGI grade, and their interaction on all-cause mortality in MV patients. This study was a secondary analysis of a multicenter, prospective, observational study that enrolled adult patients with an expected duration of mechanical ventilation ≥ 48 h from 14 general intensive care units in Zhejiang Province between March and August 2014.
View Article and Find Full Text PDFOpto-electrophysiology neural probes targeting single-cell levels offer an important avenue for elucidating the intrinsic mechanisms of the nervous system using different physical quantities, representing a significant future direction for brain-computer interface (BCI) devices. However, the highly integrated structure poses significant challenges to fabrication processes and the presence of photoelectric artifacts complicates the extraction and analysis of target signals. Here, we propose a highly miniaturized and integrated opto-electrophysiology neural probe for electrical recording and optical stimulation at the single-cell/subcellular level.
View Article and Find Full Text PDFBackground: Patients in the intensive care unit (ICU) are highly susceptible to malnutrition, and while enteral nutrition via nasogastric tube is the preferred method, there is a risk of inadvertent reflux and aspiration. Therefore, clinicians have turned to nasointestinal tubes (NET) for enteral nutrition as an alternative option. But the precise localization of NET presents an ongoing challenge.
View Article and Find Full Text PDFThe selection of highly efficient materials and the construction of advantageous structures are essential for realizing high-performance electrode materials. In this paper, electrode material CuS/C@NiMnCe-LDH/CF with excellent morphology and high performance has been successfully designed and prepared by simple hydrothermal and calcination techniques. First, ZIF-67 is loaded on the outer layer of CuS rods to obtain core-shell structured CuS@ZIF-67 rods, whose ZIF-67 MOF shell is carbonized to obtain CuS@C rods.
View Article and Find Full Text PDFPotassium (K) and magnesium (Mg) play analogous roles in regulating plant photosynthesis and carbon and nitrogen (C-N) metabolism. Based on this consensus, we hypothesize that appropriate Mg supplementation may alleviate growth inhibition under low K stress. We monitored morphological, physiological, and molecular changes in G935 apple plants under different K (0.
View Article and Find Full Text PDFEfferocytosis of apoptotic neutrophils (PMNs) by macrophages is helpful for inflammation resolution and injury repair, but the role of efferocytosis in intrinsic nature of macrophages during septic acute kidney injury (AKI) remains unknown. Here we report that CD47 and signal regulatory protein alpha (SIRPα)-the anti-efferocytotic 'don't eat me' signals-are highly expressed in peripheral blood mononuclear cells (PBMCs) from patients with septic AKI and kidney samples from mice with polymicrobial sepsis and endotoxin shock. Conditional knockout (CKO) of in macrophages ameliorates AKI and systemic inflammation response in septic mice, accompanied by an escalation in mitophagy inhibition of macrophages.
View Article and Find Full Text PDFStretchable flexible thin-film electrodes are extensively explored for developing new wearable energy storage devices. However, traditional carbon-based materials used in such independent electrodes have limited practical applications owing to their low energy storage capacity and energy density. To address this, a unique structure and remarkable mechanical stability thin-film flexible positive electrode comprising CoS nanoparticles decorated hollow CuS cubes and reduced graphene oxide (rGO), hereinafter referred to as CCSrGO, is prepared.
View Article and Find Full Text PDFSince the emergence of single-cell electroanalysis, the two-electrode system has become the predominant electrochemical system for real-time behavioral analysis of single-cell and multicellular populations. However, due to the transmembrane placement of the two electrodes, cellular activities can be interrupted by the transmembrane potentials, and the test results are susceptible to influences from factors such as intracellular solution, membrane, and bulk solution. These limitations impede the advancement of single-cell analysis.
View Article and Find Full Text PDFInflammation, caused by accumulation of inflammatory cytokines from immunocytes, is prevalent in a variety of diseases. Electro-stimulation emerges as a promising candidate for inflammatory inhibition. Although electroacupuncture is free from surgical injury, it faces the challenges of imprecise pathways/current spikes, and insufficiently defined mechanisms, while non-optimal pathway or spike would require high current amplitude, which makes electro-stimulation usually accompanied by damage and complications.
View Article and Find Full Text PDFJ Colloid Interface Sci
May 2024
Water-splitting electrocatalysis has gained increasing attention as a promising strategy for developing renewable energy in recent years, but its high overpotential caused by the unfavorable thermodynamics has limited its widespread implementation. Therefore, there is an urgent need to design catalytic materials with outstanding activity and stability that can overcome the high overpotential and thus improve the electrocatalytic efficiency. Metal-organic frameworks (MOFs) based and/or derived materials are widely used as water-splitting catalysts because of their easily controlled structures, abundant heterointerfaces and increased specific surface area.
View Article and Find Full Text PDFHerein, we reported a general and green synthetic strategy for photochromic functional alginate derivatives grafting with isoindolinone spiroxanthenes. Under mild condition, diverse 2-aminoalkyl isoindolinone spiroxanthene derivatives have been prepared from organic photochromic isobenzofuranone spiroxanthenes (including rhodamine B, rhodamine 6G and fluorescein), and grafted on alginate chains through amidation reaction using diamine as a linkage with water as a green solvent at room temperature. The photochromic properties of the fluorophores-modified polymers and the effect of pH value have been explored.
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