Metal coordinating-induced self-assembly of cyclic lipopeptides into high-performance antimicrobial supramolecules.

This study designed a green hydrothermally-chelating approach to generate robust antimicrobial complexes via metal-coordinated supramolecular self-assembly of cyclic lipopeptides (CLs). The metal ion (Ca and Zn)-coordinated CL (Ca/CL or Zn/CL complex; 1 mg/mL) demonstrated potent antibacterial activity against fungi (A. niger) and bacteria (E.

Activation of persulfate by nanoscale zero-valent iron loaded porous graphitized biochar for the removal of 17β-estradiol: Synthesis, performance and mechanism.

In this work, the porosity, graphitization and iron doping of biochar were realized simultaneously by the pyrolysis of biomass and potassium ferrate (KFeO), then the iron-doped graphitized biochar was reduced to synthesize nanoscale zero-valent iron loaded porous graphitized biochar (nZVI/PGBC). 17β-estradiol (E2) is an environmental endocrine disruptor that can cause great harm to the environment in small doses. Experiments illustrated that nZVI/PGBC (100 mg/L) could completely remove E2 (3 mg/L) within 45 min by activating sodium persulfate (PS, 400 mg/L).

Efficacy of nanoparticle encapsulation on suppressing oxidation and enhancing antifungal activity of cyclic lipopeptides produced by Bacillus subtilis.

This study examined the storage instability of cyclic lipopeptides (CLs) extracted from Bacillus subtilis culture; CLs were easily oxidized and therefore quickly lost antifungal activity during storage. Solid lipid nanoparticle (SLN) encapsulation effectively suppressed the oxidation and prolonged and enhanced the antifungal efficacy of CLs through controlled release. Thermal gravimetric analysis, X-ray diffraction, and Fourier transform infrared spectroscopy revealed that hydrophobic interactions between the fatty acid moieties of CLs and SLNs fortified the crystal structure of the CL-SLN complex, thereby improving the storage stability of the encapsulated CLs.

Micromonospora zhangzhouensis sp. nov., a Novel Actinobacterium Isolated from Mangrove Soil, Exerts a Cytotoxic Activity in vitro.

A new bacterial strain, designated HM134, was isolated from a sample of soil collected from a Chinese mangrove Avicennia marina forest. Assessed by a polyphasic approach, the taxonomy of strain HM134 was found to be associated with a range of phylogenetic and chemotaxonomic properties consistent with the genus Micromonospora. Phylogenetic analysis based on the 16s rRNA gene sequence indicated that strain HM134 formed a distinct lineage with the most closely related species, including M.

sp. nov., a novel actinobacterium isolated from sap of .

A novel, Gram-stain-positive, aerobic, non-endospore-forming, non-motile and rod-shaped bacterium designated RB2 was isolated from sap of collected in Mulei county, Xinjiang province, PR China. RB2 was able to grow at 10-45 °C (optimum 35 °C), pH 6.0-12.

A modified LC-MS/MS method to simultaneously quantify glycerol and mannitol concentrations in human urine for doping control purposes.

Glycerol and mannitol have the potential to act as plasma volume expanders and have been prohibited as masking agents by the World Anti-Doping Agency (WADA) accordingly. In this study, an improved strategy was developed and validated for the determination of urinary glycerol and mannitol levels simultaneously using a liquid chromatography/tandem mass spectrometry technique within 7min in an initial testing procedure. For confirmation, mannitol and all possible hexitols (allitol, altritol, galactitol, iditol and sorbitol) that can occur in human urine were baseline separated.