Publications by authors named "Jingjie Zeng"
Article Synopsis
- The study focuses on enhancing vital pulp therapy by using human umbilical cord mesenchymal stem cell-derived small extracellular vesicles (hUCMSC-sEVs) with lipopolysaccharide (LPS) pretreatment, which promotes inflammation control and stimulates dental pulp stem cells (hDPSCs) for dentin-pulp complex regeneration.
- A composite scaffold made of collagen sponge and self-assembling peptide nanofibers (CS/SAPNS) loaded with LPS-hUCMSC-sEVs was developed to facilitate the release of these vesicles to support hDPSC differentiation into osteogenic and angiogenic cells.
- The results showed that this composite scaffold effectively controlled the
Objective: The study is designed to understand the situation of full-term infants breastfeeding within 6 months of birth in Xi'an before the Covid-19 pandemic and analyze the influencing factors of exclusive breastfeeding.
Methods: Five hospitals in Xi'an province have been selected as research centers. Full-term infants who met the inclusion and exclusion criteria were recruited from these centers between January 1 and February 28, 2019.
Objective: The aim of this study was to evaluate the effects of exosomes derived from human umbilical cord mesenchymal stem cells (hUCMSCs-Exo) and human dental pulp stem cells (hDPSCs-Exo) on lipopolysaccharide-induced inflammation in human dental pulp stem cells.
Methods: Exosomes were extracted from the supernatant of human umbilical cord mesenchymal stem cells and human dental pulp stem cells. Lipopolysaccharide was used to establish the inflammation model in human dental pulp stem cells.
Aim: To develop and validate two aspiration prediction models in patients receiving nasogastric feeding.
Background: Aspiration is one of the most serious complications of nasogastric feeding. However, there is a lack of aspiration prediction models for nasogastric feeding.
MLK3 silence induces cervical cancer cell apoptosis via the Notch-1/autophagy network.
Clin Exp Pharmacol Physiol
September 2019
Mixed-lineage kinase 3 (MLK3), the mitogen-activated protein kinase kinase kinase (MAP3K), has been recognized as a player in tumorigenesis and oncogenic signalling, yet its detailed functions and signalling in cervical cancer have not been fully elucidated. Here, we identify that cervical cancer cells display higher mRNA and protein levels of MLK3 than normal cervical epithelial squamous cells. In HeLa and SiHa cell, MLK3 knockdown using siRNA remarkably suppressed cell survival and promoted cell apoptosis, with increased expression of the apoptosis-related protein Bax and reduced Bcl-2.
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