Publications by authors named "Jinghui Fan"

The application of organic solid-liquid phase change materials (PCMs) is limited for the leakage problem after phase change and high rigidity. In this work, a novel flexible solid-solid PCM (DXPCM) was synthesized using a block copolymerization process with polyethylene glycol (PEG) as the energy storage segment. The phase transition temperature (from 36.

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This study aimed to investigate the effects of multi-enzyme (alkaline protease, xylanase, glucanase, β-mannanase, cellulase, acid protease, glucoamylase, and α-galactosidase) on antioxidant capacity, egg quality, amino acid profiles in yolk, cecal microflora and metabolites in laying hens. A total of 384 Jingfen No.6 laying hens aged 65 weeks were randomly divided into 4 treatments groups (6 replicates per group) and fed diets containing 0, 150, 300, or 600 mg kg multi-enzyme over an 8-week feeding duration.

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This study investigated the effects of multi-enzyme supplementation on various aspects of laying hens, including laying performance, egg quality, intestinal health and digestive function. In total, 384 Jingfen No.6 laying hens at 65-week-age were randomly assigned to four distinct dietary treatments: a basal diet (CON), CON supplemented with 150 g/t multi-enzyme (T1), CON with 300 g/t multi-enzyme (T2), and 600 g/t multi-enzyme (T3).

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This experiment was aimed to investigate the effects of Phytosterol Ester (PSE) supplementation on egg weight, biochemical indices, liver immunity and gut microbiota of Hy-Line Brown laying hens during peak laying period. A total of 256 healthy Hy-Line Brown laying hens were randomly allocated into 4 groups. Laying hens in the control group were fed a basal diet (CON), while those in the experimental groups received a basal diet containing 10 mg/kg (PSE10), 20 mg/kg (PSE20), or 40 mg/kg (PSE40) mg/kg PSE, respectively.

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  • * Infection was found in domestic and wild pigeons, as well as red-necked turtledoves, but not in other wild bird species, indicating specific host preferences.
  • * Molecular analysis revealed two main genotypes (A and B) associated with wild and domestic pigeons, aiding in the understanding of the parasite's distribution and potential control measures.
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Objective: Porcine interferon-γ (poIFN-γ) and porcine granulocyte-macrophage colony-stimulating factor (poGM-CSF) are multifunctional cytokines that exhibit robust antiviral activity against porcine reproductive and respiratory syndrome virus (PRRSV). In this study, the immunoadjuvant effects of recombinant poIFN-γ-poGM-CSF fusion protein in inactivated PRRSV vaccine administered to piglets were assessed.

Animals: Twenty-eight 4-week-old specific pathogen-free piglets.

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  • The study aimed to evaluate how yacon root extracts (YREs) impact the health and egg production of laying hens over a 9-week experiment with 600 chickens divided into different groups.
  • Results showed that YREs increased feed intake, influenced egg shape, and improved eggshell strength, with specific percentages of YREs (0.8%, 1.6%, and 2.4%) having distinct effects on egg quality and microbial diversity in the hens' intestines.
  • The conclusion indicates that YREs not only enhance egg quality but also promote hen health and exhibit potential prebiotic benefits.
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The aim of this experiment was to investigate the effects of dietary Phytosterol Ester (PSE) supplementation on egg characteristics, eggshell ultrastructure, antioxidant capacity, liver function, hepatic metabolites, and its mechanism of action in Hy-Line Brown laying hens during peak laying period. A total of 256 healthy Hy-Line Brown laying hens were randomly allocated into four groups. The hens in the control group were fed a basal diet, while those in the experimental groups were fed a basal diet further supplemented with 10, 20, and 40 mg/kg PSE, respectively.

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Introduction: Numerous studies have demonstrated that C57BL/6 mice exhibit superior growth rates and overall growth performance compared to DBA mice. To investigate whether this discrepancy in growth performance is linked to the composition of gut microorganisms, we conducted fecal microbiome transplantation (FMT) experiments.

Methods: Specifically, we transplanted fecal fluids from adult C57BL/6 mice, high-fat C57BL/6 mice, and Wistar rats into weaned DBA mice (0.

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To compare the physical and chemical changes in egg whites during storage, assisting in the evaluation of differences in egg freshness between various chicken breeds, we chose 240 blue-shelled eggs (Blue group) and 240 commercial brown-shelled eggs (Brown group) that 28-week-old hens had laid. In this study, all eggs were stored at 25 °C. The egg weight, egg components' weight and proportion, Haugh Unit value and the contents of S-ovalbumin, ovomucin and lysozyme in the thick albumen (KA) and thin albumen (NA) were measured at eight time points every 3 days until the 21st day of storage.

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Trichomonas gallinae is a protozoan parasite that is the causative agent of trichomoniasis, and infects captive and wild bird species throughout the world. Although metronidazole has been the drug of choice against trichomoniasis for decades, most Trichomonas gallinae strains have developed resistance. Therefore, drugs with new modes of action or targets are urgently needed.

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Acute liver failure (ALF) refers to the occurrence of massive hepatocyte necrosis in a short time, with multiple complications, including inflammatory response, hepatic encephalopathy, and multiple organ failure. Additionally, effective therapies for ALF are lacking. There exists a relationship between the human intestinal microbiota and liver, so intestinal microbiota modulation may be a strategy for therapy of hepatic diseases.

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Circadian rhythm regulates body physiology and metabolism to adapt to the external environment. 1,3-dichloro-2-propanol (1,3-DCP) is a food pollutant formed during food processing. Our study explored whether toxicity of 1,3-DCP was related to circadian rhythm.

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Nitrogen pollution in groundwater is an environmental issue of global concern. Identifying nitrogen pollution sources and determining migration and transformation processes are the major ways to prevent and control nitrogen pollution in the groundwater on a regional scale. In this study, groundwater in the lower Wei River was investigated by combining multi-isotope tracing techniques with the SIAR hybrid model (source resolution) to trace the nitrate sources and their contribution rate to nitrogen pollution in groundwater of different geomorphological units, considering types of geomorphology as the units.

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To study the inorganic nitrogen in the process of interaction of river and groundwater and the changes in the microbial community, a vertical simulation device was used to simulate groundwater recharge to river water (upwelling) and river water recharge to groundwater (downwelling). The inorganic nitrogen concentrations in the soil and water solution as well as the characteristics of the microbial community were assessed to determine the inorganic nitrogen transformation and microbial community response in the heterogeneous interaction zone under hydrodynamic action, and the interaction mechanism between nitrogen transformation and the microbial community in the interaction zone was revealed. The removal rates of NO-N in the simulated solution reached 99.

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Porcine circovirus type 2 (PCV2) is the primary causative agent of porcine circovirus-associated diseases in swine, the most common of which are postweaning multisystemic wasting syndrome (PMWS) and porcine dermatitis and nephropathy syndrome (PDNS). To investigate the prevalence and genetic diversity of PCV2 in Hebei Province, Northern China, from 2016 to 2019, a total of 448 suspected cases of PCV2 infection were studied, and 179 samples were positive for PCV2. A pathological and histopathological examination suggested PCV2 to be cause of the observed lesions.

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  • Diabetic foot is a condition in diabetic patients caused by poor blood flow, and stem cell therapy using mesenchymal stem cells (MSCs) offers a potential new treatment, though the exact mechanisms are still unclear.
  • Exosomes, tiny vesicles secreted by MSCs, were isolated and studied to understand their role in reducing inflammation and promoting new blood vessel formation in ischemic diabetic foot tissue.
  • The research identified a specific microRNA (miRNA-21-5p) in exosomes that enhances angiogenesis by activating certain growth factor receptors and signaling pathways, suggesting it as a promising target for improving diabetic foot treatment.
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Background: Hydrogen sulfide (HS) has antihypertension and anti-inflammatory effects, and its endogenous-generation key enzyme cystathionine γ lyase (CSE) is expressed in CD4 T cells. However, the role of CD4 T-cell endogenous CSE/HS in the development of hypertension is unclear.

Methods: Peripheral blood lymphocytes were isolated from hypertensive patients or spontaneously hypertensive rats, then HS production and expression of its generation enzymes, cystathionine β synthase and CSE, were measured to determine the major HS generation system changes in hypertension.

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Background: This study will investigate the clinical efficacy of Duyiwei capsule (DYWC) for the treatment of gingivitis.

Methods: Relevant studies will be searched in PUBMED, EMBASE, Cochrane Library, WANGFANG, VIP, CBM, and CNKI from inception to the March 31, 2020 without limitations of language and publication time. All potential randomized controlled trials on the clinical efficacy of DYWC for the treatment of gingivitis will be considered.

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Porcine circovirus 3 (PCV3) is a recently identified virus that is associated with reproductive failure, porcine dermatitis and nephropathy syndrome, and multi-systemic inflammation. To investigate the molecular epidemic characteristics and genetic evolution of PCV3 in northern China, a commercial TaqMan-based real-time quantitative PCR kit was used to detect PCV3 in 435 tissue specimens collected from pigs with various clinical signs from 105 different swine farms in northern China. The results showed that 48 out of 105 (45.

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This study investigated the dietary supplementation of tea residue fermented by and , to explore its effects on growth performance, digestion performance, meat quality, serum antioxidant capacity, and intestinal morphology in pigs bred for rapid growth, also known as fatteners. One hundred and ninety-two healthy "Duroc × Landrace × Yorkshire" ternary hybrid pigs (body weight 70 ± 1.0 kg) were randomly divided into four groups according to the feeding test requirements, with four replicates in each group, and 12 fatteners per replicate.

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  • PRRSV is a virus causing significant economic losses in the swine industry, with five lineages circulating in mainland China; Lineage 3, emerging in 2005, became dominant in the south post-2010.
  • This study isolated two new strains, SD110-1608 and SDWH27-1710, from northern China in 2017 and classified them into sublineage 3.5 based on genetic analysis of their ORF 5 sequences.
  • The strains resulted from recombination of two parent strains and exhibit unique characteristics, suggesting that sublineage 3.5 may have originated from sublineage 3.2 from Taiwan, providing insights into the classification and spread of the virus
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Porcine bocavirus (PBoV), which belongs the genus Bocaparvovirus, has been identified throughout the world. However, serological methods for detecting anti-PBoV antibodies are presently limited. In the present study, an indirect enzyme-linked immunosorbent assay (PBoV-rNP1 ELISA) based on a recombinant form of nucleoprotein 1 (NP1) of PBoV was established for investigating the seroprevalence of PBoV in 2025 serum specimens collected in north-central China from 2016 to 2018, and 42.

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