Zhonghua Bing Li Xue Za Zhi
August 2015
Objective: To study the diagnostic value of SATB2, together with CK7 and CK20, in colorectal cancer.
Methods: Immunohistochemical study for SATB2, CK7 and CK20 was carried out in 210 cases of colorectal cancer tissue, 100 cases of non-colorectal cancer tissue, 90 cases of lymph node metastases and 50 cases of normal colorectal mucosa.
Results: The sensitivity and specificity of CK20+/CK7- immunophenotype for diagnosis of colorectal adenocarcinoma were 78.