TBI/Cy followed by auto-HSCT is a good choice next to allo-HSCT for patients with T-LBL/ALL.

The aim of this retrospective study was to evaluate the efficiency and safety of total body irradiation plus cyclophosphamide (TBI/Cy) followed by autogenetic hematopoietic stem cell transplantation (auto-HSCT) in T-LBL/ALL patients that cannot receive allogeneic hematopoietic stem cell transplant (allo-HSCT). Between 2013 and 2023, 24 patients received auto-HSCT following by TBI/Cy, 26 patients underwent allo-HSCT, all patients achieved completed hematopoietic reconstitution after HSCT. The progression free survival (PFS) and overall survival (OS) had no statistically significant differences between the two groups (P = 0.

Pre-Launch Spectral Calibration of the Absorbed Aerosol Sensor.

Spectral calibration consists of the calibration of wavelengths and the measurement of the instrument's spectral response function (SRF). Unlike conventional slits, the absorbed aerosol sensors (AAS) are used as a slit homogenizer, in which the SRF is not a conventional Gaussian curve. To be more precise, the SRF is the convolution of the slit function of the spectrometer, the line spread function of the optical system, and the detector response function.

A Preliminary and Evaluation of the Effect and Action Mechanism of 17-AAG Combined With Azoles Against Azole-Resistant spp.

Invasive candidiasis is the primary reason for the increased cases of mortality in a medical environment. The resistance spectra of species to antifungal drugs have gradually expanded. Particularly, the resistance spectra of are the most prominent.

Sestrin1 inhibits oxidized low-density lipoprotein-induced activation of NLRP3 inflammasome in macrophages in a murine atherosclerosis model.

Macrophages play a crucial role in the progression of atherosclerotic lesions. In the current study, we analyzed the expression and function of sestrin1 (SESN1) in the aorta macrophages in a murine atherosclerosis model. We identified high SESN1 expression in the aorta macrophages in atherosclerotic mice.