Publications by authors named "Jinghua Ma"

The Qinghai Lake National Nature Reserve (QLNNR), renowned for its abundant natural resources and diverse ecological habitats, serves as an ideal environment for ticks, thereby increasing the risk of various tick-borne pathogens (TBPs) transmission. This study aimed to investigate the prevalence of TBPs in ticks collected from Przewalski's gazelle and Tibetan sheep within the QLNNR. A total of 313 tick samples were collected from the vicinity of Qinghai Lake.

View Article and Find Full Text PDF
Article Synopsis
  • Simnotrelvir (S/R) has shown strong antiviral effects against SARS-CoV-2 and, in a recent study, effectively reduced hospitalization rates for COVID-19 in patients during XBB variant surges.
  • The study was conducted in China with 3522 adult participants diagnosed with mild to moderate COVID-19, comparing those treated with S/R to a control group not receiving antivirals.
  • Results indicated that S/R significantly lowered the incidence of COVID-19-related hospitalizations and did not result in any deaths, especially benefiting older patients and those with existing health risks.
View Article and Find Full Text PDF

Background: Pulmonary rehabilitation plays a positive role in improving exercise tolerance and reducing readmission rates in patients with chronic obstructive pulmonary disease (COPD), while the adherence of pulmonary rehabilitation in COPD patients is still poor. The active cycle of breathing techniques based on the Hope Theory is a method to enhance patients' confidence in overcoming the disease and improve the intrinsic motivation of exercise through symptom improvement such as cough and sputum evacuation ability.

Objectives: To investigate the effect of Hope Theory education combined with the active cycle of breathing techniques on pulmonary rehabilitation of COPD patients, including exercise adherence, cough and sputum evacuation ability, hope index and exercise self-efficacy.

View Article and Find Full Text PDF

Background: Ticks are ectoparasites that feed on blood and pose a threat to both the livestock industry and public health due to their ability to transmit pathogens through biting. However, the impact of factors such as bloodmeal and geographic regions on the bacterial microbiota of remains poorly understood.

Methods: In this study, we used the v3-v4 region of the 16S rRNA gene to sequence the microbiota of from eight groups (HY_M, YS_M, XH_M, LD_M, BM_M, LD_F_F, LD_F, and BM_F_F) in Qinghai Province.

View Article and Find Full Text PDF

Aim: Examine the levels of variables and explore drivers associated with shared decision-making attitudes among newly graduated nurses.

Design: This was a descriptive and cross-sectional study.

Methods: From August 2022 to October 2022, a cross-section of 216 newly graduated nurses from four comprehensive A-level hospitals in northern China was recruited using convenience sampling.

View Article and Find Full Text PDF
Article Synopsis
  • A high-quality genome of rosemary (Salvia rosmarinus) was generated, revealing 46,121 protein-coding genes and a significant genome duplication around 28.3 million years ago, enhancing understanding of its evolution and environmental adaptation.
  • Comparative analysis showed rosemary's close genetic relationship with Salvia splendens and Salvia miltiorrhiza, with 1,918 gene families expanded, 35 involved in producing antioxidant components important for environmental resilience.
  • Multi-omics analysis indicated that certain antioxidant biosynthesis genes were up-regulated during abiotic stress, demonstrating how rosemary adapts to harsh conditions by stabilizing ROS levels and supporting cell functionality through integrated metabolic processes.
View Article and Find Full Text PDF

Hepatic insulin resistance is central to the metabolic syndrome. Here we investigate the role of BTB and CNC homology 1 (BACH1) in hepatic insulin signaling. BACH1 is elevated in the hepatocytes of individuals with obesity and patients with non-alcoholic fatty liver disease (NAFLD).

View Article and Find Full Text PDF

The role of BACH1 in the process of vascular smooth muscle cell (VSMC) differentiation from human embryonic stem cells (hESCs) remains unknown. Here, we find that the loss of BACH1 in hESCs attenuates the expression of VSMC marker genes, whereas overexpression of BACH1 after mesoderm induction increases the expression of VSMC markers during in vitro hESC-VSMC differentiation. Mechanistically, BACH1 binds directly to coactivator-associated arginine methyltransferase 1 (CARM1) during in vitro hESC-VSMC differentiation, and this interaction is mediated by the BACH1 bZIP domain.

View Article and Find Full Text PDF

Introduction: Rose black spot is an economically important disease that significantly decreases flower yield. Fungicide and biological control are effective approaches for controlling rose black spot. The objective of this study was to evaluate the effect of application of biological and chemical control agents, including (GUAL210), .

View Article and Find Full Text PDF

The current study aimed to translate the Sociocultural Attitudes Towards Appearance Questionnaire-4 (SATAQ-4) into Mandarin Chinese and to examine its psychometric properties. In Study 1 (N = 842, 427 women, 415 men), exploratory factor analysis supported a 4-factor solution for the Mandarin Chinese SATAQ-4, namely Internalization: Thin/Low body fat, Internalization: Muscular/Athletic, Pressures: Family/Peers, and Pressures: Media. Evidence also supported the high internal consistency and convergent validity of the male-subject and female-subject versions of Mandarin Chinese SATAQ-4.

View Article and Find Full Text PDF
Article Synopsis
  • The transcription factor BACH1 is associated with the risk of coronary artery disease and plays a significant role in the behavior of vascular smooth muscle cells (VSMCs) after vascular injury.
  • In experiments, the absence of BACH1 in VSMCs of mice prevented their shift from a contractile to a synthetic state, reducing cell proliferation and neointimal hyperplasia following injury.
  • BACH1 works by suppressing the expression of VSMC marker genes through a mechanism involving histone methyltransferase G9a and cofactor YAP, which highlights its importance in vascular health and potential avenues for therapeutic intervention.
View Article and Find Full Text PDF

Acute myeloid leukemia (AML) is the most common type of adult acute leukemia. The pathophysiology of the disease has been studied intensively at the cellular and molecular levels. At present, cytogenetic markers are an important basis for the early diagnosis, prognostic stratification and treatment of AML.

View Article and Find Full Text PDF

Field measurements of atmospheric carbonyl compounds (carbonyls) and essential precursors of O were carried out in the urban area of Linfen City (Linfen) where serious O pollution has occurred in recent years due to its unique terrain. Carbonyls were sampled using an automatic carbonyl sampler in August 2019 to determine their pollution characteristics and sources. An average concentration of ten carbonyls was 27 ± 5.

View Article and Find Full Text PDF

South China tigers (, SC) are the most threatened tiger subspecies in the world. All the living SCs are captive in zoos or reserves and depend on artificial feeding. The composition of the gut microbiome plays an important role in sustaining the health of the host.

View Article and Find Full Text PDF

The objective of this study was to evaluate the fertilization capability of White Bengal Tiger frozen-thawed completely immotile spermatozoa after interspecific intracytoplasmic sperm injection (ICSI) with bovine oocytes. The fertilization status of presumptive zygotes was assessed 18 h after ICSI by immunofluorescence staining and confocal microscopy. The fertilization rate was 34.

View Article and Find Full Text PDF

The current study aimed to translate the Body Appreciation Scale-2 (BAS-2) into Mandarin Chinese and explore its psychometric properties with college students from the Chinese mainland. In Study 1 (N = 840, 415 women, 425 men), an exploratory factor analysis upheld the unidimensional factor structure of the Mandarin Chinese BAS-2, and McDonald's omega supported the internal consistency reliability of its scores. Evidence of construct validity of the Mandarin Chinese BAS-2 was also accrued via its positive correlations with self-esteem, self-compassion, and body satisfaction as well as negative correlations with BMI, weight discrepancy, negative affect, and body surveillance.

View Article and Find Full Text PDF

Zero waste multistage utilization of biomass from Ginkgo biloba branches (GBBs) was achieved through extraction of bioactive components, analysis of antioxidant and antibacterial activities, preparation and composition of pyrolyzate, adsorption and reuse of modified biochar. The results showed that GBBs had abundant bioactive components for potential application in the industry of food, chemical raw materials and biomedicine. Especially, the bioactive compounds in acetone extract (10 mg/mL) of GBBs identified by DPPH and ABTS had free radical scavenging abilities of 92.

View Article and Find Full Text PDF

Background: Self-directed learning (SDL) ability prepares nursing students to adapt to learning after graduation. Jiang An-li's four-dimension model of SDL ability includes the "ability of self-management, ability to apply learning strategy, ability to obtain information and ability to cooperate". Students learning in small heterogeneous groups get the opportunity to work with peers from different backgrounds.

View Article and Find Full Text PDF

Catering oil fumes are a major hazard to human health. In particular, the typical Chinese cooking style is characterised by a high temperature frying process that produces high levels of cooking oil fumes. However, limited data relating to this sector mean that national emission inventory data specific to the catering service industry do not exist.

View Article and Find Full Text PDF

Background: Multidrug resistance (MDR) frequently contributes to the failure of chemotherapeutic treatments in patients diagnosed with hepatocellular carcinoma (HCC). Revealing the molecular mechanism of MDR is indispensable for the development of effective chemotherapeutic drugs.

Purpose: Due to the low-toxicity modulators to inhibit MDR, we considered that Kanglaite (KLT) is a potential agent for reversing MDR in HCC.

View Article and Find Full Text PDF

Paenibacillus polymyxa (SQR-21) is not only a plant growth-promoting rhizobacteria, but also an effective biocontrol agent against Fusarium wilt disease of watermelon. For the better understanding and clarifying the potential mechanisms of SQR-21 to improve watermelon growth and disease resistance, a split-root methodology in hydroponic and LC-MS technology with the label free method was used to analyze the key root proteins involved in watermelon metabolism and disease resistance after the inoculation of SQR-21. Out of 623 identified proteins, 119 proteins were differentially expressed when treatment (SQR-21 inoculation) and control (no bacterial inoculation) were compared.

View Article and Find Full Text PDF

Objective: To evaluate the curative effect of electroacupuncture(EA) of Zigong (EX-CA 1) and Tianshu (ST 25) and acupuncture of Sanyinjiao (SP 6) and Guanyuan (CV 4) for perimenopausal syndrome(PMS).

Methods: Fifty-eight PMS patients were equally and randomized into acupuncture group and medication group. EA (10 Hz/50 Hz, 30 min in duration) was applied at Zigong (EX-CA 1) and Tianshu (ST 25) in combination with manual acupuncture stimulation of Sanyinjiao (SP 6) and Guanyuan (CV 4) by twirling the acupuncture needles with small amplitude and till .

View Article and Find Full Text PDF

Triptolide is a diterpene triepoxide compound extracted from the medicinal plant, Hook F. The aim of the present study was to determine whether triptolide inhibits the proliferation of breast cancer cells and to further investigate the associated molecular mechanisms. The effects of triptolide on the cell viability of three breast cancer cell lines, specifically, highly metastatic MDA-MB-231, human epidermal growth factor receptor 2-positive BT-474 and estrogen receptor-positive MCF7 cells, were measured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide and apoptosis assays.

View Article and Find Full Text PDF