TNFAIP3 affects ferroptosis after traumatic brain injury by affecting the deubiquitination and ubiquitination pathways of the HMOX1 protein and ACSL3.

The occurrence and progression of traumatic brain injury involve a complex process. The pathophysiological mechanisms triggered by neuronal damage include various forms of programmed cell death, including ferroptosis. We observed upregulation of TNFAIP3 in mice after traumatic brain injury.

Understanding the Antidepressant Mechanisms of Acupuncture: Targeting Hippocampal Neuroinflammation, Oxidative Stress, Neuroplasticity, and Apoptosis in CUMS Rats.

Depression is recognized globally as one of the most intractable diseases, and its complexity and diversity make treatment extremely challenging. Acupuncture has demonstrated beneficial effects in various psychiatric disorders. However, the underlying mechanisms of acupuncture's antidepressant action, particularly in depression, remain elusive.

The regulation mechanism of ethephon-mediated delaying of postharvest physiological deterioration in cassava storage roots based on quantitative acetylproteomes analysis.

Ethylene plays diverse roles in post-harvest processes of horticultural crops. However, its impact and regulation mechanism on the postharvest physiological deterioration (PPD) of cassava storage roots is unknown. In this study, a notable delay in PPD of cassava storage roots was observed when ethephon was utilized as an ethylene source.

Combined rectus sheath block with transverse abdominis plane block by one puncture for analgesia after laparoscopic upper abdominal surgery: a randomized controlled prospective study.

Background: Rectus sheath block (RSB) and transversus abdominis plane block (TAPB) have been shown to reduce opioid consumption and decrease postoperative pain scores in abdominal surgeries. However, there are no reports about the one-puncture technique of RSB combined with TAPB for perioperative pain management during laparoscopic upper abdominal surgery.

Methods: A total of 58 patients were randomly assigned to the control group (C), the TAP group (T), and the one-puncture technique of RSB combined with TAPB group (RT).

MePP2C24, a cassava (Manihot esculenta) gene encoding protein phosphatase 2C, negatively regulates drought stress and abscisic acid responses in transgenic Arabidopsis thaliana.

Abscisic acid (ABA) signaling plays a crucial role in plant development and response to abiotic/biotic stress. However, the function and regulation of protein phosphatase 2C (PP2C), a key component of abscisic acid signaling, under abiotic stress are still unknown in cassava, a drought-tolerant crop. In this study, a cassava PP2C gene (MePP2C24) was cloned and characterized.

Metabolic GWAS-based dissection of genetic basis underlying nutrient quality variation and domestication of cassava storage root.

Background: Metabolites play critical roles in regulating nutritional qualities of plants, thereby influencing their consumption and human health. However, the genetic basis underlying the metabolite-based nutrient quality and domestication of root and tuber crops remain largely unknown.

Results: We report a comprehensive study combining metabolic and phenotypic genome-wide association studies to dissect the genetic basis of metabolites in the storage root (SR) of cassava.

Universal Renaissance Strategy of Metal Fluoride in Secondary Ion Batteries Enabled by Liquid Metal Gallium.

All-solid-state alkali ion batteries represent a future trend in battery technology, as well as provide an opportunity for low-cost metal fluoride electrode materials, if certain intrinsic problems can be resolved. In this work, a liquid metal activation strategy is proposed in which liquid Ga elements are generated in situ and doped into the LiF crystal structure by introducing a small amount of GaF . Benefiting from these two Ga states of existence, in which the liquid metal Ga can continuously maintain conformable ion/electron-transport networks, while doped Ga in the LiF crystal structure catalyzes LiF splitting, the lithium-ion storage capacity of MnF significantly increases by 87%.

Large-Area Blade-Coated Deep-Blue Polymer Light-Emitting Diodes with a Narrowband and Uniform Emission.

Large-area polymer light-emitting diodes (PLEDs) manufactured by printing are required for flat-panel lighting and displays. Nevertheless, it remains challenging to fabricate large-area and stable deep-blue PLEDs with narrowband emission due to the difficulties in precisely tuning film uniformity and obtaining single-exciton emission. Herein, efficient and stable large-area deep-blue PLEDs with narrowband emission are prepared from encapsulated polydiarylfluorene.

Abscisic Acid Signaling in the Regulation of Postharvest Physiological Deterioration of Sliced Cassava Tuberous Roots.

Phytohormone abscisic acid (ABA) influences the shelf life of fruit, vegetables, and tubers after harvest. However, little is known about the core signaling module involved in ABA's control of the postharvest physiological process. Exogenous ABA alleviated postharvest physiological deterioration (PPD) symptoms of sliced cassava tuberous roots, increased endogenous ABA levels, and reduced endogenous HO content.

Integrated Metabolomic and Transcriptomic Analyses Reveal Novel Insights of Anthocyanin Biosynthesis on Color Formation in Cassava Tuberous Roots.

Yellow roots are of higher nutritional quality and better appearance than white roots in cassava, a crucial tropical and subtropical root crop. In this work, two varieties with yellow and white cassava roots were selected to explore the mechanisms of color formation by using comparative metabolome and transcriptome analyses during seven developmental stages. Compared with the white-rooted cassava, anthocyanins, catechin derivatives, coumarin derivatives, and phenolic acids accumulated at higher levels in yellow-rooted cassava.

Resequencing of 388 cassava accessions identifies valuable loci and selection for variation in heterozygosity.

Background: Heterozygous genomes are widespread in outcrossing and clonally propagated crops. However, the variation in heterozygosity underlying key agronomic traits and crop domestication remains largely unknown. Cassava is a staple crop in Africa and other tropical regions and has a highly heterozygous genome.

Identification and Expression Analyses of the Special 14-3-3 Gene Family in Papaya and its Involvement in Fruit Development, Ripening, and Abiotic Stress Responses.

Plant 14-3-3 proteins play key roles in regulating growth, development, and stress responses. However, little is known about this gene family in papaya (Carica papaya L.).

Identification and expression of the BAHD family during development, ripening, and stress response in banana.

The BAHD family is involved in different biological roles in plants, including secondary metabolite synthesis, improving abiotic/biotic stress resistance, and influencing fruit quality. However, the knowledge about BAHD in banana, an important fruit crop, is limited. In this study, 46 banana BAHD genes (MaBAHDs) were identified and divided into four groups according to phylogenetic analysis.

Real-time isotopic methane detection using mid-infrared spectroscopy.

A real-time, nondestructive mid-infrared (mid-IR) platform was proposed for isotopic methane detection. The measurement system consisted of a tunable mid-IR laser, a miniaturized gas chamber, and a mid-IR signal receiver. The isotope ratio of the / was identified by measuring the mid-IR spectrum at =3.

Real-time and non-destructive gas mixture analysis using linear various filter enabled mid-infrared visualization.

Real-time gas mixture analysis has been demonstrated using various linear variable filter (LVF)-enabled mid-infrared (mid-IR) visualizations. Due to the characteristic absorptions of different gases, the algorithm-enabled sensing method has the ability to detect multi-component gas mixtures noninvasively. The proposed system consisted of a broadband light source, a gas mixing and delivery chamber made by polydimethylsiloxane (PDMS), a LVF, and a real-time monitoring mid-IR camera.

Direct Root Penetration and Rhizome Vascular Colonization by Fusarium oxysporum f. sp. cubense are the Key Steps in the Successful Infection of Brazil Cavendish.

Fusarium wilt of banana, which is caused by Fusarium oxysporum f. sp. cubense, is one of the most serious diseases of banana.

A New Type of Photo-Thermo Staged-Responsive Shape-Memory Polyurethanes Network.

In this paper, we developed a photo-thermo staged-responsive shape-memory polymer network which has a unique ability of being spontaneously photo-responsive deformable and thermo-responsive shape recovery. This new type of shape-memory polyurethane network (A-SMPUs) was successfully synthesized with 4,4-azodibenzoic acid (Azoa), hexamethylenediisocyanate (HDI) and polycaprolactone (PCL), followed by chemical cross-linking with glycerol (Gl). The structures, morphology, and shape-memory properties of A-SMPUs have been carefully investigated.

The spectrum of neurological presentations in an outpatient clinic of rural Zimbabwe.

Background: Previous studies to estimate burden of neurological disorders in Africa are limited to inpatients in urban hospitals. The spectrum of neurological conditions in rural Africa remains unclear.

Objective: To determine the spectrum of neurological presentations in an outpatient setting in rural Zimbabwe.

Improved camera calibration method based on perpendicularity compensation for binocular stereo vision measurement system.

High-precision calibration of binocular vision systems plays an important role in accurate dimensional measurements. In this paper, an improved camera calibration method is proposed. First, an accurate intrinsic parameters calibration method based on active vision with perpendicularity compensation is developed.

A C2H2 zinc finger protein FEMU2 is required for fox1 expression in Chlamydomonas reinhardtii.

Chlamydomonas reinhardtii fox1 gene encodes a ferroxidase that is involved in cellular Fe uptake and highly induced during Fe deficient conditions. In an effort to identify fox1 promoter regulatory elements, an insertional library was generated in a transgenic Chlamydomonas strain (2A38) harboring an arylsulfatase (ARS) reporter gene driven by the fox1 promoter. Mutants with a defective response to low iron conditions were selected for further study.

A qualitative study of provider perspectives of structural barriers to cervical cancer screening among first nations women.

Objective: In Canada, opportunistic screening programs have successfully reduced mortality from cervical cancer; however, minority or disadvantaged groups, as well as women in northern and rural areas, are inadequately recruited by this approach. Hence, we set out to examine the structural barriers that prevent First Nations women's participation in cervical cancer screening.

Methods: Using a participatory action research approach and semistructured interview guides, we conducted in-depth interviews with 18 experienced health care professionals, 12 of whom were also community members.