Publications by authors named "Jinghao Sun"

Article Synopsis
  • - The study aimed to examine how exposure to air pollution over various time periods affects arterial stiffness in individuals with and without atherosclerotic cardiovascular disease (ASCVD).
  • - Researchers measured arterial stiffness in 765 participants, finding significant long-term associations between increased levels of fine particles and arterial stiffness, while short-term exposures showed no significant effects.
  • - The findings suggest that long-term air pollution exposure contributes to higher arterial stiffness in both groups, highlighting the importance of reducing air pollution for preventing cardiovascular issues.
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Background: The effects of air pollution on endothelial function remain unclear across populations. We aimed to use brachial artery flow-mediated dilatation (FMD) to identify demographic differences in the effects of air pollution exposure on endothelial dysfunction.

Methods: We measured FMD in 850 participants from October 2016 to January 2020.

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Background: Anatomic variations of the patent foramen ovale (PFO) are commonly observed, yet limited research has investigated their impact on clinical outcomes following transcatheter closure. We aimed to explore the association between PFO morphology and clinical outcomes.

Methods: Consecutive patients with cryptogenic stroke who underwent PFO closure were prospectively enrolled at a single center from September 2019 to April 2023.

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Background: Triglyceride-glucose (TyG) index, a simple surrogate marker for insulin resistance (IR), has been reported as an independent predictor of arterial structural damage and future cardiovascular events. The association between TyG index and endothelial dysfunction remains uncertain.

Objective: The purpose of this study was to investigate the association between TyG index and endothelial dysfunction.

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Acute respiratory distress syndrome (ARDS) is a major disease that threatens the life and health of neonates. Vitamin A (VA) can participate in early fetal lung development and affect lung immune function. Researches revealed that the serum VA level in premature infants with ARDS was lower than that in premature infants without ARDS of the same gestational age, and premature infants with VA deficiency (VAD) were more likely to develop ARDS.

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Capture-recapture (CRC) surveys are used to estimate the size of a population whose members cannot be enumerated directly. CRC surveys have been used to estimate the number of Coronavirus Disease 2019 (COVID-19) infections, people who use drugs, sex workers, conflict casualties, and trafficking victims. When -capture samples are obtained, counts of unit captures in subsets of samples are represented naturally by a contingency table in which one element-the number of individuals appearing in none of the samples-remains unobserved.

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Background: The cardiovascular risk models and subclinical atherosclerotic indicators are both recommended for cardiovascular risk stratification. The accordance between the incidence of subclinical atherosclerosis and subjects with low and moderate cardiovascular risk is unclear.

Hypothesis: Subjects with low and moderate cardiovascular risk have a lower incidence of subclinical atherosclerosis compared with subjects with high risk.

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The MYB members play important roles in development, metabolism, and stress tolerance in plants. In the current study, a total of 246 tobacco R2R3-MYB transcription factors were identified and systemically analyzed from the latest genome annotation. The newly identified tobacco members were divided into 33 subgroups together with the members.

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Genome sequencing technology has generated a vast amount of genomic and epigenomic data, and has provided us a great opportunity to study gene functions on a global scale from an epigenomic view. In the last decade, network-based studies, such as those based on PPI networks and co-expression networks, have shown good performance in capturing functional relationships between genes. However, the functions of a gene and the mechanism of interaction of genes with each other to elucidate their functions are still not entirely clear.

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From the roots of Saposhnikovia divaricata, three new compounds, divaricataesters A (1), B (2), and C (3) were isolated, along with three known compounds, cimifugin (4), (3S)-2,2-dimethyl-3,5-dihydroxy-8-hydroxymethyl-3,4-dihydro-2H,6H-benzo[1,2-b:5,4-b']dipyran-6-one (5) and 5-hydroxymethyl-furfurol (6). Their structures were established by spectral analysis and comparison with the reported data in literatures.

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