Prediction of acute coronary syndrome in patients with myeloproliferative neoplasms.

Background: Patients with myeloproliferative neoplasms (MPN) are exposed to a higher risk of cardiovascular disease, especially cardiovascular calcification. The present research aimed to analyze the clinical features and coronary artery calcium score (CACS) in MPN patients, and construct an effective model to predict acute coronary syndrome (ACS) in MPN patients.

Materials And Methods: A total of 175 MPN patients and 175 controls were recruited from the First Affiliated Hospital of Ningbo University.

The paradox of Picroside II: As a natural antioxidant, but may instead futher aggravate liver injury by exacerbating mitochondrial oxidative stress.

Background: Picroside II (PII), an iridoid glycoside extracted from the rhizomes and stems of the genus Picroside, exhibits pronounced hepatoprotective properties. Pre-administration of PII protects against acute liver injury caused by D-galactosamine (D-Gal), carbon tetrachloride (CCl), and acetaminophen (APAP). This study aimed to elucidate the ramifications of PII administration subsequent to the initiation of acute hepatic injury.

Global convergence in terrestrial gross primary production response to atmospheric vapor pressure deficit.

Atmospheric vapor pressure deficit (VPD) increases with climate warming and may limit plant growth. However, gross primary production (GPP) responses to VPD remain a mystery, offering a significant source of uncertainty in the estimation of global terrestrial ecosystems carbon dynamics. In this study, in-situ measurements, satellite-derived data, and Earth System Models (ESMs) simulations were analysed to show that the GPP of most ecosystems has a similar threshold in response to VPD: first increasing and then declining.

Evaluation of Coronary Artery Diffuse Calcification Stenosis by Corrected Coronary Opacification Difference.

Objectives: The artifacts produced by calcification on coronary computed tomographic angiography (CCTA) have a great influence on the diagnosis of coronary stenosis. The purpose of this study is to investigate the value of corrected coronary opacification (CCO) difference in the diagnosis of stenosis in diffusely calcified coronary arteries (DCCAs).

Methods: A total of 84 patients were enrolled.

Daily activity patterns and body temperature of the Oriental migratory locust, (Meyen), in natural habitat.

Current pest management techniques would benefit from understanding the behavioural rhythms of the target pest and its body temperature, a critical aspect not well studied and potentially limiting the effectiveness of biopesticides under natural conditions. This study aims 1) to understand under natural conditions the behavioural patterns of different stages of hoppers and adults of and 2) to identify the environmental factors modulating their body temperature through field observation. We carried out an intensive field sampling in two of the main locust breeding regions in China, recording the body temperature (day and night), morphological traits (stage, sex and size) and microhabitat of 953 individuals.

Clinical and Pulmonary CT Characteristics of Patients Infected With the SARS-CoV-2 Omicron Variant Compared With Those of Patients Infected With the Alpha Viral Strain.

Background: Omicron has become the dominant variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) globally. We aimed to compare the clinical and pulmonary computed tomography (CT) characteristics of the patients infected with SARS-CoV-2 Omicron with those of patients infected with the Alpha viral strain.

Methods: Clinical profiles and pulmonary CT images of 420 patients diagnosed with coronavirus disease-2019 (COVID-19) at Ningbo First Hospital between January 2020 and April 2022 were collected.

Meiosis resumption in human primordial germ cells from induced pluripotent stem cells by in vitro activation and reconstruction of ovarian nests.

Background: The differentiation of human induced pluripotent stem cells (iPSCs) into oocytes, which involves the transformation from mitosis to meiosis, has been a hotspot of biological research for many years and represents a desirable experimental model and potential strategy for treating infertility. At present, studies have shown that most cells stagnate in the oogonium stage after differentiation into primordial germ cells (PGCs) from human iPSCs.

Methods: iPSCs carrying a SYCP3-mkate2 knock-in reporter were generated by the CRISPR/Cas9 strategy to monitor meiosis status during induced differentiation from iPSCs into oocytes.

Detect and attribute the extreme maize yield losses based on spatio-temporal deep learning.

Providing accurate crop yield estimations at large spatial scales and understanding yield losses under extreme climate stress is an urgent challenge for sustaining global food security. While the data-driven deep learning approach has shown great capacity in predicting yield patterns, its capacity to detect and attribute the impacts of climatic extremes on yields remains unknown. In this study, we developed a deep neural network based multi-task learning framework to estimate variations of maize yield at the county level over the US Corn Belt from 2006 to 2018, with a special focus on the extreme yield loss in 2012.

Exploration on Scientific Research Data-Targeted Intelligent Recommendation System Using Machine Learning Under the Background of Sustainable Development.

The purpose is to provide researchers with reliable Scientific Research Data (SRD) from the massive amounts of research data to establish a sustainable Scientific Research (SR) environment. Specifically, the present work proposes establishing an Intelligent Recommendation System (IRS) based on Machine Learning (ML) algorithm and SRD. Firstly, the IRS is established over ML technology.

Tear Cytokines as Biomarkers for Acute Ocular Graft-Versus-Host Disease.

Purpose: The purpose of this study was to analyze tear cytokine and complement levels in patients diagnosed with acute ocular graft-versus-host disease (oGVHD) and examine the consistency of these levels with the severity of clinical manifestations.

Methods: Ten patients with acute oGVHD (20 eyes) were enrolled for the assessment of tear cytokine levels and ocular surface parameters, and 18 healthy people (36 eyes) were selected as the control group. The tear cytokine and complement levels were measured using microsphere-based immunoassay analysis.

[GIS-based measurement of tree ring].

Tree ring data is of significance for reconstructing climate and predicting environmental dynamics. In order to accurately measure spacing and other parameters of tree ring, we first assigned coordinate system to the scanned disc PS images based on GIS, and then completed the tree ring spacing measurement by using ENVI image classification software and GIS measuring tool. The measurement accuracy was proved by WinDENDRO tree ring analysis system.

The predictive value of coronary artery calcification score combined with bone mineral density for the 2-year risk of cardiovascular events in maintenance hemodialysis patients.

Purpose: Cardiovascular disease is the leading cause of death in maintenance hemodialysis (MHD) patients. The aim of this study is to investigate the predictive value of coronary artery calcification score (CACs) combined with bone mineral density (BMD) for the risk of cardiovascular diseases in MHD patients.

Methods: From January 2017 to January 2019, we enrolled 112 MHD patients and 112 controls in Ningbo First Hospital, and retrospectively counted the cardiovascular events in the next 2 years after enrollment.

Leaf Anthocyanin Content Retrieval with Partial Least Squares and Gaussian Process Regression from Spectral Reflectance Data.

Leaf pigment content retrieval is an essential research field in remote sensing. However, retrieval studies on anthocyanins are quite rare compared to those on chlorophylls and carotenoids. Given the critical physiological significance of anthocyanins, this situation should be improved.

[Spatiotemporal variation of growing season length of vegetation in China.].

We analyzed the variation trend of growing season length (GSL) of different periods in provinces (regions) of China and the corresponding movement velocity of GSL isolines at 150, 200, 250, 300 and 350 days, based on daily mean temperature data of 822 meteorological stations from 1951 to 2017. In this study, the definition of GSL given by the world meteorological organization was adopted, together with Slope, Hurst and Mann-Kendall indices. The results showed that the GSL in northern China changed significantly during 1951-2017.

Coffee Flower Identification Using Binarization Algorithm Based on Convolutional Neural Network for Digital Images.

Crop-type identification is one of the most significant applications of agricultural remote sensing, and it is important for yield estimation prediction and field management. At present, crop identification using datasets from unmanned aerial vehicle (UAV) and satellite platforms have achieved state-of-the-art performances. However, accurate monitoring of small plants, such as the coffee flower, cannot be achieved using datasets from these platforms.

Transverse myelitis associated with primary biliary cirrhosis: clinical, laboratory, and neuroradiological features.

Purpose: Only five patients diagnosed with transverse myelitis (TM) associated with primary biliary cirrhosis (PBC) have been reported in the literature to date. We report two additional patients with TM associated with PBC at our hospital and review all seven cases.

Materials And Methods: An association between neuromyelitis optic spectrum disease (NMOSD) and PBC is reported for the first time in one of our patients.

Forensic applicability of autosomal insertion/deletion loci in Chinese Daur ethnic group and genetic affinity evaluations between Daur group and reference populations.

In present study, we evaluated the genetic diversities of 30 insertion/deletion (InDel) loci and analyzed the genetic relationships between Daur and other comparison populations. In the studied Daur group, any two InDel loci showed no linkage disequilibrium, and all loci showed no deviations from exact tests of Hardy-Weinberg equilibrium. Insertion allele frequencies at 30 InDel loci ranged from 0.

Estimating reed loss caused by Locusta migratoria manilensis using UAV-based hyperspectral data.

Locusta migratoria manilensis has caused major damage to vegetation and crops. Quantitative evaluation studies of vegetation loss estimation from locust damage have seldom been found in traditional satellite-remote-sensing-based research due to insufficient temporal-spatial resolution available from most current satellite-based observations. We used remote sensing data acquired from an unmanned aerial vehicle (UAV) over a simulated Locusta migratoria manilensis damage experiment on a reed (Phragmites australis) canopy in Kenli District, China during July 2017.

A deep learning approach to conflating heterogeneous geospatial data for corn yield estimation: A case study of the US Corn Belt at the county level.

Understanding large-scale crop growth and its responses to climate change are critical for yield estimation and prediction, especially under the increased frequency of extreme climate and weather events. County-level corn phenology varies spatially and interannually across the Corn Belt in the United States, where precipitation and heat stress presents a temporal pattern among growth phases (GPs) and vary interannually. In this study, we developed a long short-term memory (LSTM) model that integrates heterogeneous crop phenology, meteorology, and remote sensing data to estimate county-level corn yields.

Rice Yield Estimation Using Parcel-Level Relative Spectral Variables From UAV-Based Hyperspectral Imagery.

Time-series Vegetation Indices (VIs) are usually used for estimating grain yield. However, multi-temporal VIs may be affected by different background, illumination, and atmospheric conditions, so the absolute differences among time-series VIs may include the effects induced from external conditions in addition to vegetation changes, which will pose a negative effect on the accuracy of crop yield estimation. Therefore, in this study, the parcel-based relative vegetation index () and the parcel-based relative yield are proposed and further used to estimate rice yield.

Imatinib-induced irreversible interstitial lung disease: A case report.

Rationale: Imatinib mesylate (imatinib) is a classic tyrosine kinase inhibitor used to treat chronic myeloid leukemia. Although it is well tolerated by most patients and helps in the achievement of complete remission, a few rare imatinib-associated adverse effects such as pulmonary interstitial fibrosis have been reported. Because of its rareity, the clinical features of imatinib-induced interstitial lung disease (ILD) remain unclear.

Horizontally Aligned Carbon Nanotube Based Biosensors for Protein Detection.

A novel horizontally aligned single-walled carbon nanotube (CNT) Field Effect Transistor (FET)-based biosensing platform for real-time and sensitive protein detections is proposed. Aligned nanotubes were synthesized on quartz substrate using catalyst contact stamping, surface-guided morphological growth and chemical vapor deposition gas-guided growth methods. Real-time detection of prostate-specific antigen (PSA) using as-prepared FET biosensors was demonstrated.

An extended PROSPECT: Advance in the leaf optical properties model separating total chlorophylls into chlorophyll a and b.

The PROSPECT leaf optical model has, to date, well-separated the effects of total chlorophyll and carotenoids on leaf reflectance and transmittance in the 400-800 nm. Considering variations in chlorophyll a:b ratio with leaf age and physiological stress, a further separation of total plant-based chlorophylls into chlorophyll a and chlorophyll b is necessary for advanced monitoring of plant growth. In this study, we present an extended version of PROSPECT model (hereafter referred to as PROSPECT-MP) that can combine the effects of chlorophyll a, chlorophyll b and carotenoids on leaf directional hemispherical reflectance and transmittance (DHR and DHT) in the 400-800 nm.

Mapping deforestation and urban expansion in Freetown, Sierra Leone, from pre- to post-war economic recovery.

Freetown, the capital of Sierra Leone has experienced vast land-cover changes over the past three decades. In Sierra Leone, however, availability of updated land-cover data is still a problem even for environmental managers. This study was therefore, conducted to provide up-to-date land-cover data for Freetown.

Improved synthesis and growth of graphene oxide for field effect transistor biosensors.

Reduced graphene oxide (RGO) has many advantages over graphene such as low-cost, aqueous processable and industrial-scalable. However, two main limitations that prevent the use of RGO in electronics are the high electrical resistance and large electrical resistance deviation between fabricated devices. This limits RGO's use in biosensors, capacitors and other electronic devices.