Publications by authors named "Jingdi Bai"
S100A4 mediates the accumulation and functions of myeloid-derived suppressor cells via GP130/JAK2/STAT3 signaling in acute myeloid leukemia.
Biochim Biophys Acta Mol Basis Dis
January 2025
Article Synopsis
- Acute myeloid leukemia (AML) is a serious blood cancer that is hard to treat because it weakens the immune system.
- Researchers found that a protein called S100A4 makes this problem worse in AML patients, and high levels of S100A4 were linked to poorer survival rates.
- S100A4 not only helps cancer cells avoid the immune system but also makes it harder for patients to respond to chemotherapy, so knowing about this protein can help doctors decide the best treatment for AML.
RNA N6-methyladenosine (m6A) readers mediate cancer progression. However, the functional role and potential mechanisms of the m6A readers in prostate cancer tumorigenicity remain to be elucidated. In this study, we demonstrate that YTHDF3 expression is elevated in castration-resistant prostate cancer (CRPC) and positively correlated to high grade, bone metastasis and poor survival.
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