A novel flower-shaped Ag@ZIF-67 chemiluminescence sensor for sensitive detection of CEA.

In this work, a chemiluminescence (CL) aptasensor for sensitive carcinoembryonic antigen (CEA) detection was constructed based on the CL system of luminol-HO-NaOH. Magnetic carbon nanotubes (MCNTs), as the base material, was modified with CEA-aptamer and DNA1, and was combined with the novel flower-shaped Ag@ZIF-67 of modified with DNA2 through the principle of base complementary pairing. CEA combined with aptamer when it existed in the solution.

A chemiluminescence aptasensor for sensitive detection of alpha-fetoprotein based on hemin@ZIF-67.

In this work, hemin@ZIF-67 composites were prepared and were used to construct a chemiluminescence (CL) aptasensor for alpha-fetoprotein (AFP) detection. Hemin is a catalytic porphyrin with two carboxylate groups that can covalently bond to metal ions. A hemin/ZIF-67 composite was prepared via covalent bonding between the carboxyl groups of hemin and the cobalt ion of ZIF-67, and these materials were characterized by scanning electron microscopy (SEM), infrared spectroscopy (IR), and X-ray diffraction (XRD).