Correlation of 18F-FDG PET/CT metabolic parameters with Ki-67 expression and tumor staging in nasopharyngeal carcinoma.

Purpose: The study aimed to investigate the imaging parameters of 18F-fluorodeoxyglucose (18F-FDG) PET/computed tomography (PET/CT) in nasopharyngeal carcinoma (NPC), specifically examining the relationship between mean standardized uptake value (SUVmean), maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) with Ki-67 expression, T-stage, and tumor node metastasis (TNM) stage.

Methods: A retrospective analysis was conducted on 143 consecutive NPC patients from January 2015 to December 2023 who underwent 18F-FDG PET/CT for initial disease assessment. SUVmax, SUVmean, MTV, and TLG were quantified from PET/CT images.

Enhanced detection of skull-base bone invasion in nasopharyngeal carcinoma: the supplementary diagnostic value of fluorine-sodium fluoride (F-NaF) positron emission tomography/computed tomography (PET/CT) combined with magnetic resonance imaging (MRI).

Background: Nasopharyngeal carcinoma (NPC) originates in the nasopharyngeal mucosa, the lateral wall of the nasopharynx. A significant challenge in NPC management is skull-base bone invasion (SBBI), which affects prognosis and treatment planning. Magnetic resonance imaging (MRI) is the primary diagnostic tool for SBBI in NPC patients; however, the detection of SBBI can be challenging due to skull-base complexity and overlapping MRI signals.

The potential advantages of F sodium fluoride positron emission tomography-computed tomography for clinical staging and management planning in patients with nasopharyngeal carcinoma.

Background: The staging and treatment planning of nasopharyngeal carcinoma (NPC) face challenges due to limited sensitivity of conventional imaging. F-sodium fluoride (F-NaF) positron emission tomography-computed tomography (PET/CT) offers potential advantages in detecting early bone involvement. This retrospective cohort study aimed to assess the potential advantage of F-NaF PET/CT for clinical staging and management planning in patients with NPC and to compare F-NaF PET/CT findings with those of conventional imaging modalities.

The value of F-NaF PET/CT in the diagnosis of bone metastases in patients with nasopharyngeal carcinoma using visual and quantitative analyses.

To assess the diagnostic value of F-NaF PET/CT in diagnosing bone metastases in patients with nasopharyngeal carcinoma (NPC) using visual and quantitative analyses. 164 patients with NPC who underwent F-NaF PET/CT between 2017 and 2021 were included. The sensitivity, specificity, and accuracy were calculated.

Comparison of Bone Metastases between F-NaF PET/CT, F-NaF PET, and Planar Tc-MDP Bone Scintigraphy in Patients with Newly Diagnosed Nasopharyngeal Carcinoma.

Purpose: Our study aims to compare the diagnostic value of F-NaF positron emission tomography-computed tomography (PET/CT), F-NaF PET, and planar Tc-MDP bone scintigraphy for detection of bone metastases in patients with newly diagnosed nasopharyngeal carcinoma (NPC).

Methods: Our study retrospectively analyzed 58 patients with pathologically proven NPC. They all underwent both F-NaF PET/CT and planar Tc-MDP bone scintigraphy within a 7-day interval.

Primary Malignant Melanoma of the Oropharynx Presented on 18F-FDG PET/CT.

Primary malignant melanoma in the oropharynx is extremely rare. A 49-year-old man presented with a 3-month history of progressive dysphagia. An outside CT scan of the head and neck showed a space-occupying lesion in the oropharynx.

Endotracheal, Endobronchial, and Vocal Cords Metastases From Lung Cancer Detected by 18F-FDG PET/CT.

A 61-year-old man with a history of lung cancer initially treated 3 years prior presented with a new onset of cough for 1-month and 2-week hoarseness. FDG PET/CT revealed multiple hypermetabolic lesions in the endotracheal, endobronchial, and vocal cords. Subsequently, immunostaining confirmed that all lesions were metastatic squamous cell carcinomas originating from the patient's primary lung squamous cell carcinoma.

Observer agreement and accuracy of 18F-sodium fluoride PET/computed tomography in the diagnosis of skull-base bone invasion and osseous metastases in newly diagnosed nasopharyngeal carcinoma.

Objectives: To evaluate the interobserver agreement and the diagnostic performance in F-sodium fluoride (F-NaF) PET/computed tomography (CT) for the detection of skull-base bone invasion (SBBI) and osseous metastases in patients with newly diagnosed nasopharyngeal carcinoma (NPC).

Methods: One hundred seventeen patients with newly diagnosed NPC between 2017 and 2019 who underwent F-NaF PET/CT was in included. Two experienced observers independently evaluated the F-NaF PET/CT of SBBI and osseous metastases on a patient level using a two-category scale present on a dichotomous scale, respectively.

A Rare Case of Primary Ventricular Lymphoma Presented on FDG PET/CT.

Primary ventricular lymphoma is a rare form of non-Hodgkin lymphoma confined to the central nervous system. A 51-year-old woman presented with a 4-month history of unsteady gait and progressive decline in memory. An outside brain MRI showed multiple space-occupying lesions in the ventricles, which suggested malignancy.

A Predictive Scoring Model for Short-Term Local Recurrent Nasopharyngeal Carcinoma Based on Magnetic Resonance Imaging.

Objective: To predict the early identification of recurrence based on magnetic resonance imaging (MRI) in nasopharyngeal cancer (NPC) patients.

Methods: The clinical and MRI data of 215 patients with local recurrent NPC were retrospectively reviewed. Logistic regression analysis was performed to distinguish the independent risk factors for the short-term (less than 24 months) local recurrence of NPC.