[Clinical features and prognostic of double primary carcinoma of uterine corpus and the ovary].

Objective: To investigate the clinical features, treatment and prognosis of patients with double primary carcinoma of uterine corpus and ovary.

Methods: The clinical features, operation findings, treatment and prognosis of 36 patients with double primary carcinoma of uterine corpus diagnosed and treated in the last 20 years, 25 with typical endometrial adenocarcinoma and endometrioid carcinoma of the ovary (group A) 11 with non-endometrioid carcinoma in uterine corpus and/or ovary (group B) were respectively analyzed.

Results: There was no significant difference in survival rate between the group A and group B.

[Analysis of 21 cases of epithelial ovarian malignancies in women aged below 30 years].

Objective: To study the presentation, histology type, stage of disease, treatment and outcome of epithelial ovarian malignancies in young women less than 30 years old.

Method: A total of 21 cases of epithelial ovarian malignancies in young women less than 30 years old between Jan 1986 and Mar 2002 were analyzed retrospectively.

Results: The median age at the time of diagnosis was 24 years (range 16-29 years).

[Comparison of clinical characteristics of extraovarian peritoneal serous papillary carcinoma with papillary serous ovarian carcinoma].

Objective: To study the differences of clinical characteristics between patients with extraovarian peritoneal serous papillary carcinoma (EPSPC) and those with papillary serous ovarian carcinoma (PSOC).

Methods: Fourteen patients with EPSPC and 50 patients with PSOC who were admitted to Peking Union Medical College Hospital from 1984 to 2002 were retrospectively analyzed, and their clinical features, chemosensitivities and survival rate were compared.

Results: Patients with EPSPC were significantly older than those with PSOC (mean age 62.

Laparoscopic surgery in patients with hypovolemic shock due to ectopic pregnancy.

Objective: To evaluate the feasibility and safety of operative laparoscopy for ectopic pregnancy with hypovolemic shock.

Methods: Two hundred and fifteen women with ectopic pregnancy underwent operative laparoscopy. These patients were divided into two groups.

[Primary malignant melanoma of the cervix: report of four cases and review of the literature].

Objective: To investigate the clinical and pathological characteristics of primary cervical malignant melanoma, the treatment, and prognosis.

Methods: The clinical and pathological data of four patients with primary malignant melanoma of the cervix admitted to our hospital from Sept. 1996 to Aug 2002 were analyzed retrospectively.

[Study on posterior intra-vaginal slingplasty for pelvic floor reconstruction].

Objective: To study the efficacy and safety of posterior intra-vaginal slingplasty (IVS) in the re-construction surgery of pelvic floor.

Methods: Eleven patients with vault prolapse and severe prolapse of uterus undergoing posterior IVS were prospectively studied.

Results: Average operation time was 55 min.

[Clinical and pathological analysis of intravenous leiomyomatosis].

Objective: To investigate the clinical and biological characteristics of intravenous leiomyomatosis and the treatment methods, as well as their effect on prognosis.

Methods: The clinical and pathologic data of 7 patients with intravenous leiomyomatosis of the uterus admitted to our hospital from June 1992 to June 2003 were analyzed retrospectively. All the cases were followed up.

[Correlative factors analysis of recurrence of endometriosis after conservative surgery].

Objective: To determine the correlative factors with recurrence of endometriosis after conservative surgery.

Methods: A cohort study was performed on 285 patients who had a minimum of 36 months of follow-up after conservative surgery for endometriosis. All patients underwent clinical interview, physical examination and ultrasonography.

[Clinical aspects of mature ovarian teratoma: result of 695 cases].

Objective: To evaluate the clinical aspects of mature ovarian teratoma.

Method: We retrospectively studied 695 patients operated in PUMC Hospital between January 1990 and December 2000.

Results: Laparoscopy surgery had shorter hospitalization day, less blood loss during surgery, shorter operation time compared with laparotomy (P < 0.

Estrogen receptor in pelvic floor tissues in patients with stress urinary incontinence.

Our study is to investigate the presence of estrogen receptor (ER) and its possible etiological relationship with the development of stress urinary incontinence (SUI). Thirty-one biopsy specimens from pelvic floor tissues were obtained from 31 patients categorized into three groups: pelvic organ prolapse (POP), SUI and control groups. ER in the pelvic muscles tissues was evaluated quantitatively after immunohistochemical staining to visualize the ER in the tissue.

Study on nerve fiber density in anterior vaginal epithelium for stress urinary incontinence.

The aim of this study was to determine the relationship of innervation in anterior vaginal epithelium with the etiology of stress urinary incontinence (SUI). Fifty-three biopsy specimens of the anterior vaginal epithelium were obtained from 53 subjects in control, pelvic organ prolapse (POP) and SUI groups. Routine HE staining and immunohistochemical staining for protein gene product 9.

[Epithelial ovarian tumors in adolescence: a study of clinical features and treatment].

Objective: To study the clinical feature, diagnosis and treatment of epithelial ovarian tumors in adolescent patients.

Methods: A retrospective analysis was performed on 29 patients of epithelial ovarian tumors between the age of 13 and 19 during the period of 1983 - 2002 in Peking Union Medical College Hospital. Twenty of the cases were with benign tumors, four with borderline, and five with malignant tumors.

[Relationship of cyclooxygenase 2 expression and chemotherapy response and prognosis in human ovarian carcinoma].

Objective: To investigate the relationship between expression of cyclooxygenase 2 (COX-2) and chemotherapy response and prognosis of patients with ovarian carcinoma.

Methods: The expression of COX-2 was detected by immunohistochemistry in ovarian carcinoma tissues. Correlations between COX-2 and clinicopathological markers, therapeutic effect and prognosis of the patients with ovarian carcinoma were analyzed by chi(2) test, Kplan-Meire and Cox model.

[Study of morphological changes in levator ani muscle of patients with stress urinary incontinence or pelvic organ prolapse].

Objective: To investigate the morphological characteristics of levator ani muscle in patients with stress urinary incontinence (SUI) or pelvic organ prolapse (POP) and to explore whether the alterations could contribute to pathogenesis of the diseases.

Methods: Biopsy specimens of levator ani muscle were obtained from 15 patients with SUI, 19 patients with POP and 3 asymptomatic controls with rectal cancer during operation. The structure of levator ani muscle was examined with routine histological techniques: HE staining, modified Gomori trichrome staining, NSE staining, ACP staining, and adenosine triphosphatase (ATPase) staining.

[Effect of different surgical approaches on quality of life and cost-consequence].

Objective: To evaluate the effects of total abdominal hysterectomy (TAH), laparoscopic hysterectomy (LH) and transvaginal hysterectomy (TVH) on quality of life, cost and health care utilization.

Methods: A study of women who underwent elective hysterectomy was performed to assess the effect of operations on quality of life using WHO quality of life-bref before operation, at the 4th, 14th and 28th day after operation, respectively. The data of total cost and health care utilization were also analyzed.

[Ureteral injury in gynecologic laparoscopies].

Objective: To investigate the ureteral injury in gynecological laparoscopies and discuss its diagnosis, treatment and prevention.

Methods: Ureteral injury in gynecological laparoscopies during the past 13 years was reviewed retrospectively. The clinical features of initial operations including the types of disease, uterine size, pelvic adhesion, operative procedures and the methods of diagnosis, treatment and prognosis of ureteral injury were studied.

[Comparative analysis of laparoscopic surgery and laparotomy for early stage endometrial cancer].

Objective: To evaluate the feasibility of laparoscopic surgical treatment of early stage endometrial cancer.

Methods: From January 1998 to August 2003, 24 endometrial cancer cases treated by laparoscopy were analyzed as the study group. And 41 endometrial cancer cases treated by laparotomy during the same period were randomly selected as the control group.

[Clinical analysis of endometrial carcinoma patients aged 45 years and younger].

Objective: To retrospectively analyze the clinical characteristics and outcomes of endometrial carcinoma patients aged 45 years and younger.

Methods: Fifty-two cases of endometrial carcinoma aged 45 years and younger were treated in Peking Union Medical College Hospital. They were further divided into group A (35 years of age and younger) and group B (older than 35 years).