[The differences in absorption and metabolism of bisphenol A between rats and mice].

Objective: To investigate the mechanism of the different levels of serum bisphenol A (BPA) between rat and mouse after oral administration.

Methods: A total of 18 specific pathogen free (SPF) male rats and 18 mice were treated with 300 mg/kg BPA by oral administration, blood samples were taken from rats and mice after BPA administration at 0.5, 1.

[The time-concentration relationship of serum bisphenol A in male rats].

Objective: To investigate the relationship of time-concentration of bisphenol A (BPA) in male Sprague-Dawley (SD) rats after single oral BPA administration.

Methods: A total of 66 specific pathogen free (SPF) SD male rats were divided into 10 experimental groups and control group (n = 6). The experimental group rats were treated with BPA of 300 mg/kg by oral gavage and blood samples were taken from one group at 0.