Knockdown of ubiquitin‑specific peptidase 39 inhibits the malignant progression of human renal cell carcinoma.

Ubiquitin specific peptidase 39 (USP39) serves important roles in mRNA processing and is involved in tumorigenesis of multiple solid malignancies. However, the influence and underlying mechanism of USP39 on human renal cell carcinomas (RCC) remain to be elucidated. The current study investigated the functional roles of USP39 in human RCC cell lines.

[Early and mid-term results of endovascular aneurysm repair for infrarenal abdominal aortic aneurysm].

Objective: Endovascular aneurysm repair (EVAR) of abdominal aortic aneurysms (AAA) has become a viable alternative to open surgical repair in the last decade. We report here our experience on the mid-term results of EVAR and analysis of the outcomes associated with endograft AAA repair.

Methods: Between Nov 2002 and Mar 2007, 26 patients with AAA were enrolled in a single institution.

Phosphatidylcholine-specific phospholipase C activity and level increase evidently in thromboangitis obliterans.

Thromboangitis obliterans (TAO) is considered to be an inflammatory disease. Previous research has demonstrated that phosphatidylcholine-specific phospholipase C (PC-PLC) plays critical roles in various inflammatory responses. However, the connection between PC-PLC and TAO is undetermined.