Publications by authors named "Jing-xian Lu"
Objective: To study the effects of decreased leptin expression on liver fibrosis.
Methods: The small interfering RNA, targeting leptin gene, was designed according to the secondary structure of leptin gene. The recombinant plasmids were encapsulated with lipofectamine and then injected into carbon tetrachloride (CCl4) induced rat liver fibrosis models.
[Effects of antisense RNA of connective tissue growth factor expressing plasmid on rat liver fibrosis].
Zhonghua Gan Zang Bing Za Zhi
February 2007
Objective: To observe the effects of antisense RNA of connective tissue growth factor (CTGF) on rat liver fibrosis.
Methods: Gene recombinant techniques were used to construct a rat antisense RNA of CTGF recombinant plasmid which could be expressed in eukaryotic cells. The recombinant plasmids were encapsulated with lipofectamine and then transducted into a carbon tetrachloride (CCl4) induced rat liver fibrosis model.