Chromosomal imbalances revealed in primary renal cell carcinomas by comparative genomic hybridization.

Renal cell carcinoma (RCC) accounts for approximately 3% of all new cancer cases. Although the classification of RCC is based mainly on histology, this method is not always accurate. We applied comparative genomic hybridization (CGH) to determine genomic alterations in 46 cases of different RCC histological subtypes [10 cases of clear cell RCC (CCRCC), 13 cases of papillary RCC (PRCC), 12 cases of chromophobe RCC (CRCC), 9 cases of Xp11.

Lutein has a protective effect on hepatotoxicity induced by arsenic via Nrf2 signaling.

Arsenic produces liver disease through the oxidative stress. While lutein can alleviate cytotoxic and oxidative injury, nuclear factor erythroid 2-related factor 2 (Nrf2) pathway plays a critical role in defending oxidative species. However, the mechanisms by which lutein protects the liver against the effect of arsenic are not known.

[Association of lipoprotein lipase gene Hind III and S447X polymorphisms in metabolic syndrome patients among Kazakh and Han ethnics from Xinjiang].

Objective: To investigate the association of lipoprotein lipase gene Hind III and S447X polymorphisms with metabolic syndrome among Kazakh and Han ethnicities in Xinjiang.

Methods: PCR-RFLP was used to detect 802 subjects' lipoprotein lipase Hind III and S447X genotypes (including 201 controls and 200 metabolic syndrome patients in Kazakh and Han ethnicities, respectively).

Results: (1) Frequencies of H+H-/H-H- genotype (32.

[Analysis on the changing trends of non-communicable diseases in Xinjiang Production and Construction Corps, from 1998 to 2008].

Objective: To understand the changing trends of non-communicable diseases (NCDs) in Xinjiang Production and Construction Corps from 1998 to 2008.

Methods: A stratified-cluster random sampling based cross-sectional NCDs survey was carried out in 2008, and using the data of NCDs from the health service surveys in 1998 and 2004, in Xinjiang Production and Construction Corps. The prevalence rate of NCDs was standardization according to age proportion of the population being surveyed in 1998.