Gastrodin ameliorates cognitive dysfunction in diabetes by inhibiting PAK2 phosphorylation.

Diabetes is associated with higher prevalence of cognitive dysfunction, while the underlying mechanism is still elusive. In this study, we aim to explore the potential mechanism of diabetes-induced cognitive dysfunction and assess the therapeutic effects of Gastrodin on cognitive dysfunction. Diabetes was induced by a single injection of streptozotocin.

1,3-Bis(2-anilino-2-oxoeth-yl)-1H-imidazol-3-ium chloride dimethyl-formamide monosolvate.

In the imidazolium cation of the title compound, C19H19N4O2(+)·Cl(-)·C3H7NO, the dihedral angles between the imidazole ring and the phenyl rings are 85.86 (4) and 70.26 (5)°.

A new tridentate pincer phosphine/n-heterocyclic carbene ligand: palladium complexes, their structures, and catalytic activities.

A new imidazolium salt, 1,3-bis(2-diphenylphosphanylethyl)-3H-imidazol-1-ium chloride (2), for the phosphine/N-heterocyclic carbene-based pincer ligand, PC(NHC)P, and its palladium complexes were reported. The complex, [Pd(PC(NHC)P)Cl]Cl (4), was prepared by the common route of silver carbene transfer reaction and a novel direct reaction between the ligand precursor, PC(NHC)P.HCl and PdCl(2) without the need of a base.