Publications by authors named "Jing-Xuan Tang"
Article Synopsis
- The study investigates how the interaction between growth hormone receptors impacts cell repair and fertility in hamster infertility models.
- Grinodin and 2Y were tested, showing Grinodin resulted in significantly higher birth rates compared to human menopausal gonadotropin (hMG) and human growth hormone (hGH).
- Grinodin promoted the growth of ovarian stem cells and follicles while reducing negative hormonal effects, suggesting its potential as a more effective treatment for fertility than 2Y, hMG, or hGH.
Erratum to: The treatment effect of novel hGHRH homodimer to male infertility hamster.
Korean J Physiol Pharmacol
January 2019
[This corrects the article on p. 637 in vol. 22, PMID: 30402024.
View Article and Find Full Text PDFThe treatment effect of novel hGHRH homodimer to male infertility hamster.
Korean J Physiol Pharmacol
November 2018
Extra-hypothalamic growth hormone-releasing hormone (GHRH) plays an important role in reproduction. To study the treatment effect of (a novel hGHRH homodimer), the infertility models of 85 male Chinese hamsters were established by intraperitoneally injecting 20 mg/kg of cyclophosphamide once in a week for 5 weeks and the treatment with or human menopausal gonadotropin (hMG) as positive control was evaluated by performing a 3-week mating experiment. 2-8 mg/kg of and 200 U/kg of hMG showed similar effect and different pathological characteristics.
View Article and Find Full Text PDFExtra-hypothalamic growth hormone-releasing hormone (GHRH) plays an important role in infertility. The female infertility models were formed by intraperitoneally injecting cyclophosphamide in 5-week-old Chinese hamster once in a week for 5 weeks. All the models mated with healthy male hamster in the ratio of 1:1 in the experimental 6-8th week and the couples were separated to breed in the 9-10th week.
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