Publications by authors named "Jing-Xing Jiang"
[Sleep-improving mechanism of Chaiqin Ningshen Granules in insomnia rats: based on hippocampal metabonomics].
Zhongguo Zhong Yao Za Zhi
April 2022
Article Synopsis
- - The study uses advanced mass spectrometry techniques to investigate how Chaiqin Ningshen Granules (CNG) affect the metabolism of insomnia rats, specifically focusing on a liver depression syndrome model induced by parachlorophenylalanine (PCPA).
- - By analyzing the hippocampus of the rats, the research finds that CNG significantly improves symptoms of insomnia, enhances neurotransmitter levels like serotonin and GABA, and identifies 27 potential biomarkers associated with insomnia.
- - The metabolic pathway analysis indicates that CNG and estazolam influence multiple metabolic pathways, suggesting their effectiveness in alleviating insomnia through the regulation of key metabolites.