Publications by authors named "Jing-Wen Fang"
Article Synopsis
- Bone or brain metastases occur in 20-40% of late-stage non-small-cell lung cancer (NSCLC) patients, leading to a poor median survival of 4-6 months, yet the distinctions in metastatic types at the single-cell level remain underexplored.
- A comprehensive analysis of 14 biopsy samples from treatment-naïve advanced NSCLC patients revealed significant differences in cancer-associated fibroblast (CAF) populations among the bone, brain, and intrapulmonary metastases.
- The study highlights the role of specific CAF subpopulations in promoting either bone or brain metastasis and suggests potential therapeutic targets by disrupting their interactions with tumor cells to inhibit metastasis.
Objective: To investigate the value of optic disc retinal nerve fiber layer (RNFL) thickness in the diagnosis of diabetic peripheral neuropathy (DPN).
Methods: Ninety patients with type 2 diabetes, including 60 patients without DPN (NDPN group) and 30 patients with DPN (DPN group), and 30 healthy participants (normal group) were enrolled. Optical coherence tomography (OCT) was used to measure the four quadrants and the overall average RNFL thickness of the optic disc.
The reaction of F2 + C3H6 has been investigated with the crossed molecular beam technique. The only observed primary product channel is F + C3H6F while the HF + C3H5F channel cannot be found. The reaction cross section was measured as a function of collision energy and the reaction threshold was determined to be 2.
View Article and Find Full Text PDFThe reaction of F(2)+C(2)H(4) has been investigated with crossed molecular beam experiments and high level ab initio calculations. For a wide range of collision energies up to 11 kcal/mol, only one reaction channel could be observed in the gas phase. The primary products of this channel were identified as F+CH(2)CH(2)F.
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