Publications by Jing-Shu Li

Publications by authors named "Jing-Shu Li"

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[Preimplantation Genetic Diagnosis of α/β Complex Thalassemia by Next Generation Sequencing].

Tian-Wen He Jian Lu Chuang-Qi Chen Wei-Ning Zhou Jing-Shu Li Li DU

Zhongguo Shi Yan Xue Ye Xue Za Zhi

August 2021

Objective: To explore the application value of next generation sequencing (NGS) in preimplantation genetic diagnosis of α/β complex thalassemia couple.

Methods: The coding regions of α-globin genes (HBA1, HBA2) and β-globin gene (HBB) were selected as the target regions. The high-density and closely linked single nucleotide polymorphism (SNP) sites were selected as the genetic linkage markers in the upstream and downstream 2M regions of the gene.

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