Publications by authors named "Jing-Ruo Zhang"
This study was conducted to examine the effects of acupuncture on gut microbiota and expression of NLRP3 inflammasome in the colon in poststroke depression (PSD) model rats. Sprague-Dawley male rats were randomized into four groups: sham surgery group, poststroke depression group, acupuncture group, and probiotics group. Acupuncture therapy at Baihui (GV20), Shenting (GV24), bilateral Zusanli (ST36) acupoints in the acupuncture group and probiotic gavage therapy in the probiotics group were performed once per day for 2 weeks.
View Article and Find Full Text PDFMoxibustion ameliorates cerebral ischemia-reperfusion injury by regulating ferroptosis in rats.
Clin Exp Pharmacol Physiol
October 2023
Article Synopsis
- Moxibustion is shown to be effective in treating acute cerebral infarction, but its specific mechanism is not fully understood.
- This study examined the effects of moxibustion on cerebral ischemia-reperfusion injury (CIRI) in rats, comparing it to a control group and another treatment with ferrostatin-1.
- Results indicated that moxibustion reduces nerve damage and neuronal death by regulating lipid metabolism, lowering iron levels in the brain, and inhibiting ferroptosis, thereby offering protective benefits to brain cells after CIRI.
Objective: This systematic review and meta-analysis aimed to assess the clinical efficacy of acupuncture in late-life depression (LLD).
Methods: A comprehensive search of seven electronic databases was conducted from inception to November 2022, including the Cochrane Library, PubMed, Embase, CNKI, VIP, CBM and the Wan Fang database. All data analysis were conducted by Revman 5.
Does urinary metabolite signature act as a biomarker of post-stroke depression?
Front Psychiatry
August 2022
Background: It is difficult to conduct the precise diagnosis of post-stroke depression (PSD) in clinical practice due to the complex psychopathology of depressive disorder. Several studies showed that gas chromatography-mass spectrometry (GC-MS)-identified urinary metabolite biomarkers could significantly discriminate PSD from stroke survivors.
Methods: A systematic review was performed for the keywords of "urinary metabolite" and "PSD" using Medline, Cochrane Library, Embase, Web of Science, PsycINFO, Wanfang, CNKI, CBM, and VIP database from inception to 31 March 2022.
[Analgesic Effect and Mechanism of Electroacupuncture on Rats with Chronic Inflammatory Pain].
Zhongguo Zhong Xi Yi Jie He Za Zhi
June 2016
Objective: To observe analgesic effect of electroacupuncture ( EA) on rats with chronic inflammatory pain and its regulatory mechanism on ispilateral dorsal root ganglion (DRG) and spinal dorsal horn (SDH) Mas-related G protein-coupled C receptor (MrgprC).
Methods: Totally 40 healthy male SD rats were divided into 4 groups according to random number table, i.e.