Arthroscopic Linear Chain Fixation for the Treatment of Medial Meniscus Posterior Root Tear: A Case Study.

Background: The repair and reconstruction of medial meniscus posterior root tears (MMPRTs) is an important issue in the field of orthopedic sports medicine. This study reports the first application of arthroscopic linear chain fixation for the treatment of MMPRTs.

Case Presentation: A 78-year-old female patient presented with a 1.

Prospective randomized comparison of knee stability and joint degeneration for double- and single-bundle ACL reconstruction.

Purpose: This study aims to determine the outcome of double-bundle anterior cruciate ligament (ACL) reconstruction using an allograft in comparison with ACL reconstruction using a double-bundle autograft or a single-bundle allograft.

Methods: A total of 424 patients who accepted primary ACL reconstructions were divided randomly into three groups: double-bundle technique with autograft (DB-AU group, n = 154), double-bundle technique with allograft (DB-AL group, n = 128), and single-bundle technique with allograft (SB group, n = 142). The KT-1000 arthrometer and pivot-shift tests were performed at 3, 12, and 36 months after surgery, and clinical outcome measurements include the Lysholm score and the IKDC rating scales.

Effects of myogenin on muscle fiber types and key metabolic enzymes in gene transfer mice and C2C12 myoblasts.

Skeletal muscle fiber type composition is one of the important factors influencing muscle growth and meat quality. As a member of the myogenic transcription factors, myogenin (MyoG) is required for embryonic myoblast differentiation, but the expression of MyoG continues in mature muscle tissue of adult animals, especially in oxidative metabolic muscle, which suggests that MyoG may play a more extended role. Therefore, using MyoG gene transfer mice and C2C12 myoblasts as in vivo and in vitro models, respectively, we elected to study the role of MyoG in muscle fiber types and oxidative metabolism by using overexpression and siRNA suppression strategies.

[Experimental research on repairing full-thickness articular cartilage defects by transplantation of autologous uncultured bone-marrow-derived mononuclear cells in combination with micro-fracture].

Objective: To examine the feasibility of autologous uncultured bone-marrow-derived mononuclear cells (BM-MNCs) in combination with microfracture in a full-thickness articular cartilage defect model so as to provide experimental rationales for clinical applications.

Methods: A total of 40 rabbits were divided randomly into groups A, B, C and D (n = 10 each). In groups A and C, 5 ml marrow samples were harvested from left femur and then autologous BM-MNCs isolated.

[Anterior cruciate ligament reconstruction using periosteum wrapped autologous hamstring tendons: clinical research].

Objective: To develop a surgical technique using a periosteal flap wrapped autologous hamstring tendons in ACL reconstruction and to examine its short-term outcome.

Methods: A total of 110 patients (110 knees) were included. The experimental group (n = 52) received ACL reconstruction with hamstring tendons wrapped in periosteum.

[Effect of increased posterior tibial slope or partial posterior cruciate ligament release on knee kinematics of total knee arthroplasty].

Objective: To compare the effects of increased posterior tibial slope or partial posterior cruciate ligament (PCL) release on knee kinematics of total knee arthroplasty (TKA).

Methods: Anteroposterior laxity, rotational laxity, varus and valgus laxity and maximum flexion angle were evaluated in 6 normal cadaver knees and the knees after TKA at flexion 0 degrees , 30 degrees , 60 degrees , 90 degrees and 120 degrees . Then the femoral prosthesis was shifted 5 mm posteriorly to simulate the tightly implanted knee.

[The incidence and variation of tunnel enlargement after anterior cruciate ligament reconstruction].

Objective: To investigate the incidence and variation of tunnel enlargement after anterior cruciate ligament (ACL) reconstruction.

Methods: ACL reconstructions using hamstring tendons were performed in 58 patients (58 knees) in the study. MRI scans were taken in a consistent manner at 1, 3, 6, 12 and 24 months after surgery to measure tibial and femoral tunnel expansion.