Publications by authors named "Jing-Pu Yang"
Primary diffuse large B-cell lymphoma of the ethmoid sinus: a case report.
Ear Nose Throat J
August 2014
B-cell lymphoma of the paranasal sinuses is rare. We present the case of a 42-year-old woman who presented with proptosis, diplopia, and vision disturbances in the right eye. She was diagnosed with diffuse large B-cell lymphoma of the ethmoid sinus.
View Article and Find Full Text PDFObjective: To investigate the inhibitory effect of plasmid-based survivin-specific short hairpin RNA and GRIM-19 on the growth of Hep-2 laryngeal cancer cells.
Methods: The plasmid expressing survivin-specific short hairpin RNA (shRNA) and GRIM-19 (p-siRNA survivin/GRIM-19) was prepared and transfected into Hep-2 cells with Lipofectamine 2000. The mRNA and protein expression of surviving and GRIM-19 were measured with RT-PCR and western blot assay, respectively.
Background: Mounting evidence suggests that tumors are histologically heterogeneous and are maintained by a small population of tumor cells termed cancer stem cells. CD133 has been identified as a candidate marker of cancer stem cells in laryngeal carcinoma. This study aimed to analyze the chemoresistance of CD133(+) cancer stem cells.
View Article and Find Full Text PDF[Suppressing the growth of Hep-2 human laryngeal cancer cells by silencing survivin gene in vitro and in vivo].
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
August 2010
Article Synopsis
- The study aimed to investigate how silencing the protein survivin affects the growth of Hep-2 human laryngeal cancer cells both in the lab (in vitro) and in living organisms (in vivo).
- Researchers used a specific siRNA to reduce survivin levels, leading to a significant decrease in cell proliferation and a reduction in tumor size in mice.
- The results showed that survivin silencing resulted in decreased tumor growth and increased cancer cell death, indicating its potential as a therapeutic target for laryngeal cancer.