TRIM25 contributes to the malignancy of acute myeloid leukemia and is negatively regulated by microRNA-137.

Background: Acute myeloid leukemia (AML) is a ubiquitous malignancy that occurs in the hematological system. Tripartite motif-containing 25 (TRIM25) has been found to be involved in various carcinomas comprising AML. However, the function and underlying causative role of TRIM25 in AML are still obscure.

Comparison of the Efficacy of Nilotinib and Imatinib in the Treatment of Chronic Myeloid Leukemia.

Objective: To compare the efficacy of nilotinib and imatinib in the treatment of chronic myeloid leukemia (CML).

Study Design: Analytical study.

Place And Duration Of Study: Department of Hematology, Chongqing Three Gorges Central Hospital, China, from January 2016 to January 2018.