Publications by authors named "Jing-Ling Han"
Article Synopsis
- Identifying biomarkers for early cancer detection is crucial for improving diagnosis and treatment outcomes, specifically focusing on esophageal squamous cell carcinoma (ESCC) in this study.
- Researchers analyzed DNA methylation patterns in cancer cells and plasma cell-free DNA from early-stage ESCC patients to construct a reliable methylation profile.
- Seven specific CG sites showed significant hypermethylation in three genes (CASZ1, CDH13, and ING2), demonstrating 100% sensitivity and specificity for potential non-invasive diagnosis of esophageal cancer through blood samples.
Objective: Blood pressure (BP) load, defined as the percentage of abnormally elevated BP readings, is usually provided on the report of ambulatory BP monitoring. However, the usefulness of BP load is still uncertain. In the present study, we examined whether BP load would be associated, independently of BP level, with target organ damage.
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