[Screening of key genes and pathways of ischemic stroke and prediction of traditional Chinese medicines based on bioinformatics].

The aim of this paper was to explore the key genes and pathogenesis of ischemic stroke(IS) by bioinformatics, and predict the potential traditional Chinese medicines for IS. Based on the gene-chip raw data set of GSE22255 from National Center of Biotechnology Information(NCBI), the article enrolled in 20 patients with ischemic stroke and 20 sex-and age-matched controls, and differentially expressed genes(DEGs) were screened based on R language software. The DAVID tool and R language software were used to perform gene ontology(GO) biological process enrichment analysis and Kyoto encyclopedia of genes and gnomes(KEGG) pathway enrichment analysis.

Effects of electro-acupuncture at Tongli (HT 5) and Xuanzhong (GB 39) acupoints from functional magnetic resonance imaging evidence.

Objective: To explore the specifificity of Tongli (HT 5) and Xuanzhong (GB 39) paired acupionts in aspects of Deqi sensation and brain activation patterns during electroacupuncture.

Methods: In this study, 15 healthy subjects were enrolled. All participants suffered two kinds of functional magnetic resonance imaging (fMRI) examinations randomly: Examination A received electro-acupuncture (EA) at the bilateral Tongli (HT5) and Xuanzhong (GB 39) acupoints (ACU), and examination B received EA at bilateral non-acupoints (NAP).

[An overview of researches on underlying mechanisms of acupuncture therapy by functional magnetic resonance imaging in recent 5 years].

In the present paper, the authors review the development of researches on acupuncture therapy with functional magnetic resonance imaging (fMRI) in recent 5 years in both China and foreign countries. The current researches mainly involve 1) specificity of efficacies of acupoints, 2) mechanisms of acupuncture intervention underlying improvement of various clinical conditions or illnesses, 3) individual difference of the subjects, and 4) sustained efficacies of acupuncture. In the early stage, researches on acupuncture therapy mostly focus on the immediate efficacy and the specificity of efficacies of acupoints.

[Present situation and thinking of studies on apoplectic aphasia].

There were different emphasis between Chinese medicine and Western medicine in the study of apoplectic aphasia, the study of Chinese medicine lay particular emphasis on treatment with more interfering methods but lacking unifying evaluation criteria; while studies of Western medicine lay particular emphasis on studies of mechanisms, classification and language rehabilitation of aphasia, etc.. Selection and application of scientific study methods are key to attain expectation results of studies, and deeply make studies of apoplectic aphasia, so as to explore and establish the model of integrated Chinese and western medicine study of aphasia, promote rehabilitation of language function and increase life quality of the patient of apoplexy.