[Integrin 3 mRNA changes after orthodontic teeth movement in periodontitis rats].

Objective: To study the integrin beta3 mRNA changes after orthodontic treatment on normal teeth and periodontitis teeth in rats.

Methods: 96 adult SD rats of 10 weeks old were randomly divided into normal tooth move-ment group and periodontitis tooth movement group. The rats in the two groups were sacrificed after 0 d, 12 h, 1 d, 3 d, 5 d and 7 d of tooth movement.

[Association of estrogen receptor gene polymorphisms and primary trigeminal neuralgia].

Objective: To investigate the association of estrogen receptor (ER) gene polymorphism and primary trigeminal neuralgia.

Methods: By polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), ER gene polymorphism was analyzed in 20 trigeminal neuralgia (TR) patients and 20 control individuals, and the distribution of ER genotype was compared in TR group and control group.

Results: There was no significant difference in frequencies of allele and genotype in XbaI or PvuII polymorphism or XbaI with PvuII polymorphisms together between TR group and control group (P > 0.

[Effects of orthodontic force on tumor necrosis factor alpha protein expression in the inflammatory periodontal tissues].

Objective: To explore the combined effects of orthodontic force and inflammation on the remodelling of periodontal tissues.

Methods: The upper first molars underwent mesial orthodontic force on 48 rats suffering experimental periodontitis and 48 rats injected lipopolysaccharide, respectively.

Results: The TNF-alpha protein expression in the compressed periodontal tissues fluctuated during 0, 2, 12 hours and 2, 7, 14 days stages, the OD value got to the peak in the compressed periodontal tissues in 2 days.

[The integrin beta1 mRNA changes after orthodontic movement of teeth in periodontitis rats].

Objective: To study the integrin beta1 mRNA changes after orthodontic tooth movement in normal teeth and periodontitis teeth of rats.

Methods: The OD of positively stained osteoclasts for integrin beta1 mRNA using in situ hybridzation was detected after orthodontic tooth movement in normal teeth and periodontitis teeth groups.

Results: Integrin beta1 mRNA expression were detected on all osteoclasts in tooth movement samples of normal and periodontitis teeth.