Publications by authors named "Jing-Jie Ciou"
Article Synopsis
- The study investigates how high salt intake influences the progression of autoimmune diseases, specifically type 1 diabetes, using nonobese diabetic (NOD) mice as models.
- Findings indicate that a high-salt diet (HSD) accelerates diabetes development and worsens autoimmune responses, notably through a mechanism involving CD4+ T cells.
- The research highlights the critical role of SPAK, a protein that appears to be key in linking high salt consumption to increased T-cell activity and diabetes severity, suggesting potential therapeutic avenues targeting SPAK might mitigate this effect.
