Publications by authors named "Jing-Hua Liang"

Peripheral nerve injury (PNI) involving the loss of sensory and movement functions is challenging to repair. Although the gold standard of PNI repair is still the use of autologous nerve grafts, the destruction of the donor side is inevitable. In the present study, peripheral nerve tissueoids (PNTs) composed of a Schwann cell (SC)-based neurotrophin-3 (NT-3) delivery system and a decellularized optic nerve (DON) with naturally oriented channels were engineered to investigate the mechanism of PNTs in nerve regeneration.

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Article Synopsis
  • Autophagy is a cellular recycling process that helps manage damaged components, playing a crucial role in heart health through three forms: macro-autophagy, micro-autophagy, and chaperone-mediated autophagy.
  • Regulation of autophagy in heart cells (cardiomyocytes) is essential during stress conditions like ischemia, leading to myocardial remodeling, which can cause heart failure.
  • This review highlights recent findings on autophagy's protective effects against cardiac remodeling, the underlying molecular mechanisms, potential new treatments, and future challenges in applying autophagy research to heart disease.
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Background: Colorectal cancer is one of the most common cancers worldwide with high mortality and is classified as a single entity, although colon cancer and rectal cancer have largely different diagnoses, treatments, surgical methods, and recurrence rates. ≥ 16-slice spiral computed tomography (SCT) is mostly applied to detect the local stage of colon cancer; however, its diagnostic accuracy and whether it is conducive to distinguishing between high-risk and low-risk colon cancer are unclear.

Aim: To systematically review the diagnostic accuracy of ≥ 16-slice SCT for local staging of colon cancer.

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