Publications by authors named "Jing-Han Gao"
Phage therapy offers a promising approach to combat the growing threat of antimicrobial resistance. Yet, key questions remain regarding dosage, administration routes, combination therapy, and the causes of therapeutic failure. In this study, we focused on a novel lytic phage, ФAb4B, which specifically targeted the Acinetobacter baumannii strains with KL160 capsular polysaccharide, including the pan-drug resistant A.
View Article and Find Full Text PDFThe rise of antimicrobial resistance in ESKAPEE pathogens poses significant clinical challenges, especially in polymicrobial infections. Bacteriophage-derived endolysins offer promise in combating this crisis, but face practical hurdles. Our study focuses on engineering endolysins from a phage, fusing them with ApoE23 and COG133 peptides.
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- Elastomers are crucial in both traditional industries and emerging tech fields, but they often suffer damage from electricity, heat, and force during use.
- There's a need for new elastomer materials that maintain strong mechanical properties while being self-healing and environmentally friendly, despite challenges achieving this balance.
- A new type of elastomer, made from carbon hydrazide and polydimethylsiloxane, shows impressive self-healing efficiency, high stretchability, and recyclability, making it a promising material for applications like flexible strain sensors.
Recent studies have demonstrated that hyperglycemia is a major risk factor for the development and exacerbation of cardiovascular disease (CVD). However, the molecular mechanisms involved in diabetic cardiomyopathy (DCM) have not been fully elucidated. In this study, we focused on the underlying mechanism of DCM.
View Article and Find Full Text PDFAlthough an increasing number of studies have reported that telemonitoring (TM) in patients with chronic obstructive pulmonary disease (COPD) can be useful and efficacious for hospitalizations and quality of life, its actual utility in detecting and managing acute exacerbation of COPD (AECOPD) is less established. This meta-analysis aimed to identify the best available evidence on the effectiveness of TM targeting the early and optimized management of AECOPD in patients with a history of past AECOPD compared with a control group without TM intervention. We systematically searched PubMed, Embase, and the Cochrane Library for randomized controlled trials published from 1990 to May 2020.
View Article and Find Full Text PDF[Investigation of knowledge, attitude and practice (KAP) of foodborne parasitic diseases among senior high school students in Zigui County].
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi
February 2017
Objective: To understand the status of knowledge, attitude and practice (KAP) of foodborne parasitic diseases among senior high school students in Three Gorges Reservoir Region.
Methods: A total of 1 353 senior high school students were selected with the cluster sampling method and investigated with the questionnaires in Zigui County, and the data were analyzed statistically.
Results: Among the 1 353 students surveyed, the awareness rates of parasitic diseases, their hazards and transmissions were 62.