Publications by authors named "Jing-Guo Chen"
Aim: Bitter taste is sensed by the bitter taste receptor (TAS2R), which is mainly expressed in the tongue as well as in extra-oral organs, such as the gastrointestinal tract, respiratory tract, brain, heart and testis. This study aimed to investigate whether TAS2R is expressed in the mesenteric, cerebral and omental arteries.
Main Methods: The expression levels of TAS2R mRNA and protein were determined by reverse-transcription polymerase chain reaction and Western blotting, respectively.
Cyclosporine A (CsA) induces hypertension after transplantation. Hydrogen sulfide (HS) was found to have hypotensive/vasoprotective effects in the cardiovascular system. The present study aims to investigate the role of HS on CsA-induced vascular function disorder in rats.
View Article and Find Full Text PDFWith the biomolecule glutathione (GSH) as a capping ligand, Eu(3+)-doped cadmium sulfide composite nanoparticles were successfully synthesized through a straightforward one-pot process. An efficient fluorescence energy transfer system with CdS nanoparticles as energy donor and Eu(3+) ions as energy accepter was developed. As a result of specific interaction, the fluorescence intensity of Eu(3+)-doped CdS nanoparticles is obviously reduced in the presence of Hg(2+).
View Article and Find Full Text PDFArticle Synopsis
- An efficient fluorescence energy transfer (FET) system was developed using CePO(4):Tb(3+) nanocrystals as the donor and 6-mercapto-5-triazole[4,3-b]-S-tetrazine as the acceptor, effectively facilitating the transfer of energy for analytical applications.
- The synthesis of CePO(4):Tb(3+) nanocrystals was accomplished through aqueous solutions, and their properties were examined using advanced microscopy and spectroscopy techniques.
- This system enabled a sensitive and selective fluorescence method for detecting formaldehyde in water, showing a linear response across a wide concentration range and a low detection limit, outperforming other methods in selectivity and sensitivity.
Background: It is unclear whether edge segments have different responses to paclitaxel eluting stent (PES) and sirolimus eluting stent (SES) implantation in patients with unstable angina. This study aimed to compare the different vascular edge responses in patients with unstable angina and single de novo coronary lesion treated with SES and PES.
Methods: Two hundred and fifty-five patients with unstable angina and single de novo lesion were randomly assigned to PES and SES groups.