Wnt7a promotes muscle regeneration in branchiomeric orbicularis oris muscle.

Background: The orbicularis oris muscle exhibits a deficiency in cleft lip patients. Compared with the somite-derived limb muscles, the regeneration performance of the branchiomeric orofacial muscle has seldom been investigated.

Objective: This study aims to explore the possibility of augmenting the orbicularis oris muscle through the stimulus of Wnt7a.