Five new C-diterpenoid alkaloids from Delphinium pachycentrum Hemsl. and Delphinium majus Ulbr. as potential acetylcholinesterase inhibitors.

Two new C-diterpenoid alkaloids, named pachycenines F-G (1-2), along with three known diterpenoid alkaloids (3-5), were extracted from the whole plant of Delphinium pachycentrum Hemsl. Additionally, three new C-diterpenoid alkaloids, majuszine A-C (6-8), along with twenty-four known compounds (9-32) were isolated from the whole plant of Delphinium majus Ulbr. The structures of all these compounds were identified using IR, HR-ESI-MS, 1D and 2D NMR.

The study of influence factors on (131)I treatment of differentiated thyroid carcinoma with lymph node metastases.

Objective: Thyroid carcinoma is the most common malignant endocrine tumor, which comprises 1% in all human tumors. As for differentiated thyroid carcinoma (DTC), lymph nodes are the most common metastatic site for which the major treatment is (131)I therapy. This retrospective study aimed to investigate the therapeutic effect and analyze the influence factors on (131)I treatment of DTC with lymph node metastases.

Evaluation of radionuclide cerebrospinal fluid scintigraphy as a guide in the management of patients with hydrocephalus.

Purpose: Radionuclide cerebrospinal fluid scintigraphy (RCFS) has long been clinically applied in the diagnosis of hydrocephalus. This study aims to evaluate the clinical value of RCFS as a guide in the management of patients with hydrocephalus.

Methods: Thirteen patients with hydrocephalus were investigated.

The role of single-photon emission computed tomography/computed tomography for precise localization of metastases in patients with differentiated thyroid cancer.

Purpose: It is very important in the management of patients with differentiated thyroid cancer (DTC) to precisely localize the foci of I-131 uptake, but it is difficult because of a lack of anatomic landmarks. The purpose of this study was to investigate the added value of I-131 single-photon emission computed tomography (SPECT)/computed tomography (CT) fusion imaging using a hybrid system in patients with DTC.

Methods: Ninety-four patients with DTC underwent I-131 SPECT/CT using a hybrid tomography consisting of a dual-head variable-angle gamma camera and a low-dose X-ray tube.

Comparison of whole-body 18F-FDG SPECT and posttherapeutic 131I scintigraphy in the detection of metastatic thyroid cancer.

Purpose: The usefulness of fluorine 18 fluorodeoxyglucose ((18)F-FDG) imaging in differentiated thyroid cancer (DTC) has been demonstrated by investigators. The aim of this study is to compare the ability of fluorodeoxyglucose (FDG)-single photon emission computed tomography (SPECT) to detect metastatic DTC with posttherapeutic iodine131 ((131)I) scintigraphy.

Methods: 239 patients (78 men, 161 women; age range, 23-76 years, mean 45 years); All patients underwent FDG-SPECT and (131)I whole-body scan.