Publications by authors named "Jing-Chong Dong"

As an important chitin-modifying enzyme, chitin deacetylase (CDA) has been characterized in many fungi, but its function in the entomopathogenic fungus Beauveria bassiana remains unclear. Three CDAs with conserved domains of the carbohydrate esterase 4 (CE-4) family were identified in B. bassiana.

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Ndt80-like transcription factor Ron1 is best known for its essential role in the regulation of N-acetylglucosamine (GlcNAc) catabolism. Ron1 was again found to be essential for sensing GlcNAc in Beauveria bassiana. Importantly, our study revealed that Ron1 is involved in the metabolic processes of chitin and asexual development.

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Article Synopsis
  • - The study explored the effective dose of dexmedetomidine for preventing emergence agitation (EA) in older patients undergoing major surgery under general anesthesia.
  • - A sample of 50 geriatric patients was tested, and the median effective dose (ED50) determined was 0.30 μg·kg·h, with a predicted effective dose (ED95) of 0.42 μg·kg·h to manage EA.
  • - Results indicated a significant increase in bradycardia (slow heart rate) among patients treated with dexmedetomidine when EA was not present, highlighting a major side effect of the medication.
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