Publications by authors named "Jing-Chang Chen"

Aim: To ascertain the bioactivity and to analyse quantificationally the denervating action of botulinum toxin A (BTXA) in gel.

Methods: 36 Sprague-Dawley rats were randomized into four groups. In group A - D, the gastrocnemius muscle of one leg was randomly selected to receive injection of BTXA solution 5U in 0.

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Objective: To investigate the clinical features, diagnosis and the management of masked bilateral superior oblique palsy (MBSOP).

Methods: Retrospectively analyzed the records of all 7 patients that met the clinical criteria for MBSOP in Zhongshan Ophthalmic Center between 1999 and 2003. The head tilt, vertical deviation in primary position and the action of obliquus pre- and postoperatively were collected in detail.

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Objective: To investigate the effect of weakening the superior oblique muscles on the status of ocular torsion.

Methods: Twenty-nine patients (58 eyes) underwent tenotomy or partial ectomy of bilateral superior oblique muscles for treatment of superior oblique overacting. Objective cyclodeviations were assessed by fundus photograph before and 7 days after the surgery.

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Objective: To investigate the efficiency of interleukin-1alpha on intraocular pressure reduction and its safety.

Methods: 35 New Zealand female rabbits were randomized into seven groups. In group-A, one eye was randomly selected to receive sub-conjunctival injection of 15 ng IL-1alpha, and in group B-D, one eye was injected intracamerally with IL-1alpha 1.

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Objective: To investigate the features and treatment of V patterns strabismus.

Methods: Pre- and post-operative deviation and oblique muscle action as well as binocular visual function were evaluated in sixty-three V pattern patients. The difference between upgaze and downgaze of deviation were recorded before and after operation.

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Objective: To understand the clinical significance of subjective and objective examination of cyclodeviations and investigate the effect of weakening inferior oblique muscles on the status of ocular torsion.

Methods: Twenty patients (40 eyes) with overacting inferior oblique muscles underwent bilateral myotomy or partial myectomy of inferior oblique muscles. Subjective cyclodeviations were measured before surgery as well as one week, two months after surgery by double maddox rod test (DMRT).

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