Nitro substituent caused negative impact on occurrence and development of atherosclerotic plaque by PM-bound polycyclic aromatic compounds.

PM exposure is a significant risk factor for the occurrence and development of atherosclerosis. Polycyclic aromatic hydrocarbons (PAHs) play prominent roles in PM-related toxicity. However, the nitrated derivatives of PAHs, nitrated polycyclic aromatic hydrocarbons (NPAHs), have strong oxidizing properties due to the nitro substituents.

Prevalence and risk factors for dementia in the Tibetan region: A population-based cross-sectional study.

Background: As China's population ages, the nationwide prevalence of dementia is increasing. However, the epidemiology of dementia among the Tibetan population remains unclear.

Objective: A cross-sectional study was conducted involving 9116 participants aged >50 years in the Tibetan population to investigate the risk factors and prevalence of dementia among this population.

Protective Effect of Tangshen Formula () on Interstitial Cells of Cajal in Colon of Diabetic Rats.

Objective: To explore the effect of Tangshen Formula (, TSF), a Chinese herbal medicine, on interstitial cells of Cajal (ICC) in the colon of diabetic rats.

Methods: Fifty-four male Wistar rats were randomly divided into normal control (NC, n=14) and high-fat diet (HFD) groups (n=40). After 6 weeks, the rats in the HFD group were injected intraperitoneally streptozotocin once (30 mg/kg).

[Orographic Influences on the Spatial Distribution of PM on the Fen-Wei Plain].

Topography not only has an effect on the spatial distribution of pollutants by restricting populations and industrial activities, but also affects the formation, transmission, accumulation, diffusion, and sedimentation of PM. Topography is, therefore, an essential variable for understanding the spatial distribution of PM, especially in basin areas. Based on gridded data and both natural and human indexes, this paper examines orographic effects on the distribution of PM on the Fen-Wei Plain based on the change point method, regression, the geographical detector method, and bivariate spatial autocorrelation.

[Factors and Their Interaction Effects on the Distribution of PM in the Yangtze River Delta Based on Grids].

Spatial features of PM concentration in the Yangtze River Delta in 2016 were analyzed using remote sensing data. Selecting factors among meteorology, topography, vegetation, and emission list of air pollutants, factors and their interaction effects on the spatial distribution of PM concentration were studied based on GAM, with an evaluation unit of 0.25°×0.

The Psychological Impact of the COVID-19 Epidemic on Guangdong College Students: The Difference Between Seeking and Not Seeking Psychological Help.

Background: Coronavirus disease 2019 (COVID-19) has considerably psychologically impacted Chinese college students. Several types of online mental health services were widely implemented for college students during the outbreak. This study investigated the relationship between college students' mental health status and psychological help-seeking behavior to test the phases-decision-making model (PDM).

Mental health status and change in living rhythms among college students in China during the COVID-19 pandemic: A large-scale survey.

• 7.7% of college students showed depressive symptoms during the COVID-19 pandemic. • College students with depressive symptoms had low regulatory emotional self-efficacy.

[Influencing Factors of Ozone Concentration in Xi'an Based on Generalized Additive Models].

Based on the ozone monitoring data from 2014 to 2018, we presented the variation of ozone concentration in Xi'an and revealed the effects of ozone concentration by meteorological factors based on the generalized additive model (GAM). The results showed that ① with increasing ozone concentration year by year, the assessment standard of ozone pollution was overtaken by three consecutive years since 2016. However, the rising trend was slowed down since 2017 as a result of the strengthened pollution control during summer.

[Evolution of the Distribution of PM Concentration in the Yangtze River Economic Belt and Its Influencing Factors].

Intensive social and economic activity has led to serious pollution in the Yangtze River economic belt since 2000. It is urgent to study the evolution of the distribution of PM concentration and its influencing factors in this area, to adopt new ways of development into practice and promote comprehensive regional air pollution prevention and control. Based on PM concentration estimated by remote sensing retrieval, this paper studied the evolution of the distribution of PM concentration in the Yangtze River economic belt from 2000 to 2016, and analyzed spatial non-stationarity of the influence of natural and socio-economic factors on this evolution via a geographically weighted regression model.

E. coli diversity: low in colorectal cancer.

Background: Escherichia coli are mostly commensals but also contain pathogenic lineages. It is largely unclear whether the commensal E. coli as the potential origins of pathogenic lineages may consist of monophyletic or polyphyletic populations, elucidation of which is expected to lead to novel insights into the associations of E.

The Chemosensory Pleasure Scale: A New Assessment for Measuring Hedonic Smell and Taste Capacities.

Anhedonia, or the inability to experience pleasure, is a key clinical feature of many mental disorders such as depression and schizophrenia. Although various valid measurements of anhedonia and pleasure experience exist, no scales exist that quantify smell and taste pleasure experiences. The Chemosensory Pleasure Scale (CPS) was therefore designed to assess the hedonic capacity for smell and taste pleasure.

[Spatial-temporal Variation of Ozone Concentration and Its Driving Factors in China].

Based on the ozone monitoring data from 2015 to 2017, this study presents the spatial-temporal variation of the ozone concentration and its driving factors in major cities in China via Kriging interpolation, spatial autocorrelation analysis, hotspot analysis, and geographical detector. The results show that:① The ozone pollution became increasingly heavier from 2015 to 2017, with the number of cities in which the 90th percentile of daily maximum 8-h ozone concentration exceeded the air quality standard (GB 3095-2012) increased from 74 to 121, and the proportion of non-attainment days increased from 5.2 percent to 8.

Dysbiosis of the Gut Microbiome in Lung Cancer.

Lung cancer (LC) is one of the most serious malignant tumors, which has the fastest growing morbidity and mortality worldwide. A role of the lung microbiota in LC pathogenesis has been analyzed, but a comparable role of the gut microbiota has not yet been investigated. In this study, the gut microbiota of 30 LC patients and 30 healthy controls were examined via next-generation sequencing of 16S rRNA and analyzed for diversity and biomarkers.

[Pollution Characteristics and Emission Factors of VOCs from Vehicle Emissions in the Tianjin Tunnel].

The pollution characteristics and emission factors (EFs) of the volatile organic compounds (VOCs) of vehicles were investigated using the tunnel test method on weekdays and weekends in the Wujinglu Tunnel in Tianjin, China. Gas samples in the tunnel were collected with 3.2 L stainless steel canisters and 99 VOCs species were analyzed by gas chromatography-mass spectrometry (GC-MS).

Comparison of Chang Run Tong and Forlaxin Treatment of Constipation in Elderly Diabetic Patients.

Objective: Constipation is quite common and has impact on life quality in the elderly diabetic patients; therefore it is important to seek better treatments. The aim of this study is to evaluate the effect of Chang Run Tong (CRT) decoction on constipation in elderly diabetic patients in comparison with the effect of Macrogol 4000 powder (Forlax).

Design: This study was designed as a prospective study consisting of two parallel arms: CRT group and Forlax group.

Ambulatory blood pressure variability within the first 24 hours after admission and outcomes of acute ischemic stroke.

Our purpose was to evaluate the value of blood pressure variability within the first 24 hours after admission in predicting outcomes of patients with acute ischemic stroke (AIS). A greater variability in systolic blood pressure (adjusted odds ratio [OR] = 1.801, 95% confidence interval [CI] = 1.

Advanced glycation end-product expression is upregulated in the gastrointestinal tract of type 2 diabetic rats.

Aim: To investigate changes in advanced glycation end products (AGEs) and their receptor (RAGE) expression in the gastrointestinal (GI) tract in type 2 diabetic rats.

Methods: Eight inherited type 2 diabetic rats Goto-Kakizak (GK) and ten age-matched normal rats were used in the study. From 18 wk of age, the body weight and blood glucose were measured every week and 2 wk respectively.

Integrated butanol recovery for an advanced biofuel: current state and prospects.

Butanol has recently gained increasing interest due to escalating prices in petroleum fuels and concerns on the energy crisis. However, the butanol production cost with conventional acetone-butanol-ethanol fermentation by Clostridium spp. was higher than that of petrochemical processes due to the low butanol titer, yield, and productivity in bioprocesses.

Changes of phasic and tonic smooth muscle function of jejunum in type 2 diabetic Goto-Kakizaki rats.

Aim: To generate phasic and tonic stress-strain curves for evaluation of intestinal smooth muscle function in type 2 diabetic rats during active and passive conditions.

Methods: Seven diabetic Goto-Kakizaki (GK) male rats, 32-wk old (GK group), and 9 age-matched normal Wistar rats (Normal group) were included in the study. Jejunal segments were distended up to a pressure of 10 cm H2O in an organ bath containing 37 °C Krebs solution with addition of carbachol (CA).

[A case-control study on the duration of sleeping and cerebral infarction].

Objective: To explore the relationship between duration of sleeping and cerebral infarction.

Methods: A case-control study involved 1037 cerebral infarction patients admitted by the Second Affiliated Hospital of Harbin Medical University,December 2011-December 2012 as cases. Another 1205 adults free from cerebro-vascular diseases who had undergone physical examination in the hospital at the same period, were served as controls.

Animal models of pancreatitis: can it be translated to human pain study?

Chronic pancreatitis affects many individuals around the world, and the study of the underlying mechanisms leading to better treatment possibilities are important tasks. Therefore, animal models are needed to illustrate the basic study of pancreatitis. Recently, animal models of acute and chronic pancreatitis have been thoroughly reviewed, but few reviews address the important aspect on the translation of animal studies to human studies.

[Inhibitory effects of doxycycline on argyrophilic nucleolar organizing regions and a-smooth muscle actin expression in proliferative bovine corneal myofibroblasts in vitro].

Objective: To investigate the effect of doxycycline on the nucleolar organizing regions and a-smooth muscle actin expression in bovine corneal myofibroblasts in vitro and assess its contribution to ocular surface repair mechanisms.

Methods: Cell culture and identification: bovine corneal fibroblasts were cultured after the stroma was incubated in 1.0 and 2.

[Effect of promoter polymorphism of organic cation transporter OCTN1/2 on the susceptibility to Crohns disease: a Meta-analysis].

Objective: To investigate the associations between polymorphisms of organic cation transporter OCTN1/2 (organic cation transporter 1/2) and the susceptibility of Crohn's disease (CD) through a meta-analysis.

Methods: Databases of PubMed, EMBASE, MedLine, and CNKI (Chinese), Wanfang (Chinese) were searched for published case control studies on the association between polymorphisms of OCTN1/2 gene and the susceptibility of CD which were published before September 2012. The meta-analysis was applied with Review Manager 4.