Novel Semiconductive Ternary Hybrid Heterostructures for Artificial Optoelectronic Synapses.

Synaptic devices that mimic biological synapses are considered as promising candidates for brain-inspired devices, offering the functionalities in neuromorphic computing. However, modulation of emerging optoelectronic synaptic devices has rarely been reported. Herein, a semiconductive ternary hybrid heterostructure is prepared with a D-D'-A configuration by introducing polyoxometalate (POM) as an additional electroactive donor (D') into a metalloviologen-based D-A framework.

Differential Diagnosis of DCIS and Fibroadenoma Based on Ultrasound Images: a Difference-Based Self-Supervised Approach.

Differentiation of ductal carcinoma in situ (DCIS, a precancerous lesion of the breast) from fibroadenoma (FA) using ultrasonography is significant for the early prevention of malignant breast tumors. Radiomics-based artificial intelligence (AI) can provide additional diagnostic information but usually requires extensive labeling efforts by clinicians with specialized knowledge. This study aims to investigate the feasibility of differentially diagnosing DCIS and FA using ultrasound radiomics-based AI techniques and further explore a novel approach that can reduce labeling efforts without sacrificing diagnostic performance.

Donor-Acceptor Hybrid Heterostructures: An Emerging Class of Photoactive Materials with Inorganic and Organic Semiconductive Components.

Just as the heterojunctions in physics, donor-acceptor (D-A) heterostructures are an emerging class of photoactive materials fabricated from two semiconductive components at the molecular level. Among them, D-A hybrid heterostructures from organic and inorganic semiconductive components have attracted extensive attention in the past decades due to their combined advantages of high stability for the inorganic semiconductors and modifiability for the organic semiconductors, which are particularly beneficial to efficiently achieve photoinduced charge separation and transfer upon irradiations. In this review, by analogy with the heterojunctions in physics, a definition of the D-A heterostructures and their general design and synthetic strategies are given.

Impact of diffusion methods and metal cations on photochromic three-component D-A hybrid heterostructures.

D-A hybrid heterostructures are an attractive class of hybrid complexes composed of semiconducting organic and inorganic components, which make them potential candidates for applications in the photoelectric fields, particularly as photochromic materials. Herein, we report that the combination of metal cations (M = Zn2+ or Cd2+), silicomolybdic anions, and N,N-di(4-pyridyl)-1,4,5,8-naphthalene diimide (DPNDI) via two diffusion methods (A and B) led to four three-component D-A hybrid heterostructures with silicomolybdic anions as electron donors, and one-dimensional (1-D) naphthalenediimide coordination networks of different metal cations, [Zn2(DPNDI)2(H2O)4]·(SiMo12O40) (1-A and 1-B) and [Cd2(DPNDI)2(H2O)4]·(SiMo12O40) (2-A and 2-B), as electron acceptors. Although the different diffusion methods, 1-B, 2-A and 2-B, are isostructures with close cell parameters.

[The regulatory mechanism of Raf/MEK/ERK pathway on the rat cardiac hypertrophy induced by transverse aortic constriction].

Objective: To investigate the mRNA, protein expression levels and the phosphorylation levels of key factors in rapidly accelerated fibrosarcoma/mitogen-activated protein kinase kinase/extracellular regulated protein kinases (Raf/MEK/ERK) pathway, and to clarify the regulatory function of Raf/MEK/ERK pathway in myocardial hypertrophy.

Methods: Twenty SD rats were divided into sham-operated group and model group. The myocardial hypertrophy model was established by transverse aortic constriction (TAC).

Partially cystic thyroid cancer on conventional and elastographic ultrasound: a retrospective study and a machine learning-assisted system.

Background: Thyroid carcinoma constitutes the vast majority of all thyroid cancer, most of which is the solid nodule type. No previous studies have examined combining both conventional and elastic sonography to evaluate the diagnostic performance of partially cystic thyroid cancer (PCTC). This retrospective study was designed to evaluate differentiation of PCTC from benign partially cystic nodules with a machine learning-assisted system based on ultrasound (US) and elastography.

Molecular Dynamics, Phase Transition and Frequency-Tuned Dielectric Switch of an Ionic Co-Crystal.

Dielectric switches that can be converted between high and low dielectric states by thermal stimuli have attracted much interest owing to their many potential applications. Currently one main drawback for practical application lies in the non-tunability of their switch temperatures (T ). We report here an ionic co-crystal (Me NH) [Ni(NCS) ] that contains a multiply rotatable Me NH ion and a solely rotatable one due to a more spacious supramolecular cage for the former one.

[Preparation and Determination of Insulin-like Growth Factor I in Deer Antler, Heart and Blood].

Objective: To optimize the method for preparation of the insulin-like growth factor I (IGF-I ) in deer antler, and to determine the IGF-I in deer antler, heart and blood.

Methods: Ultrasonic extraction was used to extract IGF-I from different tissues of deer with ammonia-ammonium acetate buffer, followed by ultrafiltration and solid phase extraction to concentrate and purify the samples. At the same time, ethanol precipitation method was carried out in the purification of IGF-I ultrafiltratein deer antler, a parallel test proceeded and radio immune assay (RIA) was set to determine the IGF-I in deer antler, heart and blood.

Tissue distribution and excretion study of neopanaxadiol in rats by ultra-performance liquid chromatography quadrupole time-of-flight mass spectrometry.

Neopanaxadiol (NPD), a major ginsenoside in Panax ginseng C. A. Meyer (Araliaceae), was reported to have neuroprotective effect.

[Influence factors for prognosis in patients with acute oral poisoning with paraquat].

Objective: To investigate the influential factors for the prognosis in patients with paraquat poisoning.

Methods: Retrospective analysis was performed on 40 patients with acute paraquat poisoning to evaluate serum urea nitrogen, creatinine, alanine aminotransferase, and aspartate aminotransferase levels and organ injuries.

Results: Among the patients, 21 had lung injury, 26 had kidney injury, 13 had multiple organ dysfunction syndrome, and 12 died.

[Applied study on clustering of variables around latent components method in wavelength region selection with near-infrared spectroscopy].

The present paper introduced the principle of clustering of variables around latent components method, and used this method in selecting spectrum range of the NIR quantitative analysis models. Taking tobacco samples as experiment materials, we dealed with 107 sample spectra, divided the spectra into 5 clusters, and explained the information reflected by each of these 5 clusters in terms of chemistry. On this basis, we chose the corresponding wavelength range to set up the quantitative models of the total sugar, reducing sugar and nicotine by PLS method.

Theoretical study on the reaction of SiH(CH(3))(3) with SiH(3) radical.

The multiple-channel reactions SiH(3) + SiH(CH(3))(3) --> products are investigated by direct dynamics method. The minimum energy path (MEP) is calculated at the MP2/6-31+G(d,p) level, and energetic information is further refined by the MC-QCISD (single-point) method. The rate constants for individual reaction channels are calculated by the improved canonical variational transition state theory with small-curvature tunneling correction over the temperature range of 200-2400 K.

Determination of noradrenaline and dopamine in Chinese herbal extracts from Portulaca oleracea L. by high-performance liquid chromatography.

A simple, rapid and accurate high-performance liquid chromatographic (HPLC) technique coupled with photodiode array (PDA) detection was developed for the simultaneous determination of noradrenaline (NA) and dopamine (DA) in Chinese herbal plant extracts from the different parts of Portulaca oleracea L. The effects of various parameters, such as sodium dodecyl sulfate (SDS) concentration, pH value and proportion of methanol on chromatographic behavior of the analytes (NA and DA) were investigated. Separation of NA and DA was achieved within 10 min by a mobile phase consisting of 70% (v/v) methanol and 0.